EC Number   |
Inhibitors |
Structure |
|---|
   2.7.3.2 | Pb2+ |
lead inhibits in vitro the cytosolic and mitochondrial creatine kinase activity at 0.2 mM and that this inhibition is prevented by addition cysteamine to the assay at 0.1 mM and 0.5 mM final concentration |
   |
| 2.7.3.2 | 5,5'-dithiobis(2-nitrobenzoate) |
less than 5% residual activity at 0.1 mM |
|
| 2.7.3.2 | quercetin |
mechanism, role of radicals |
|
| 2.7.3.2 | formate |
mimics the phosphoryl group in the transition state |
|
| 2.7.3.2 | nitrate |
mimics the phosphoryl group in the transition state |
|
| 2.7.3.2 | nitrite |
mimics the phosphoryl group in the transition state |
|
| 2.7.3.2 | more |
no effect: trans-[RuCl2(4-pyridinecarboxylic acid)4] |
|
| 2.7.3.2 | bovine serum albumin |
no influence on enzyme activity |
|
| 2.7.3.2 | (2Z)-3-butyl-1-phenyl-2-(phenyltellanyl)oct-2-en-1-one |
organotellurium inhibits creatine kinase activity by two different mechanisms: competition with ADP and oxidation of critical sulfhydryl groups for the functioning of the enzyme |
|
| 2.7.3.2 | iodoacetamide |
protection by MgATP2-, MgADP-, urea |
|
