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Synonyms
ck, creatine kinase, ck-mb, creatine phosphokinase, creatine kinase-mb, creatinine kinase, creatine kinase mb, ck-bb, plasma creatine kinase, mitochondrial creatine kinase,
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adenosine triphosphate-creatine transphosphorylase
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adenosine-5'-triphosphate: creatine phosphotransferase
ATP-creatine transphosphorylase
ATP: creatine N-phosphotransferase
ATP:creatine phosphotransferase
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BB-type creatine kinase
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brain type creatine kinase
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brain-type creatine kinase
creatine kinase MB
isoform
creatine kinase muscle type
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creatine kinase-MB
isozyme
creatine N-phosphotransferase
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creatine phosphokinase
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creatine phosphotransferase
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creatinine kinase MB
isoform
kinase, creatine (phosphorylating)
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mitochondrial creatine kinase
MM-type creatine kinase
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muscle type creatine kinase
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muscle-type creatine kinase
phosphocreatine kinase
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recombinant human brain-type creatine kinase
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adenosine-5'-triphosphate: creatine phosphotransferase
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adenosine-5'-triphosphate: creatine phosphotransferase
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ATP-creatine transphosphorylase
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ATP-creatine transphosphorylase
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ATP-creatine transphosphorylase
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ATP-creatine transphosphorylase
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ATP-creatine transphosphorylase
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ATP: creatine N-phosphotransferase
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ATP: creatine N-phosphotransferase
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B-type creatine kinase
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B-type creatine kinase
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BB-CK
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BB-CK
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brain-type cytosolic isoform of creatine kinase
BCK
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brain creatine kinase
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brain creatine kinase
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brain creatine kinase
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brain-type CK
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brain-type creatine kinase
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brain-type creatine kinase
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brain-type creatine kinase
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brain-type creatine kinase
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CK
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CK MM
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CK-B
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CK-BB
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CK-MB
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CK-MM
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ckb
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CKM
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creatine kinase
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creatinine kinase
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MCK
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mitochondrial creatine kinase
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mitochondrial creatine kinase
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mitochondrial creatine kinase
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MM-CK
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MM-CK
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muscle form of creatine kinase
MtCK
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muscle creatine kinase
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muscle creatine kinase
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muscle-type creatine kinase
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muscle-type creatine kinase
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muscle-type creatine kinase
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muscle-type creatine kinase
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plasma creatine kinase
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sMiCK
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uMtCK
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additional information
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the enzyme is a member of the phosphagen (guanidino) kinase family
additional information
the enzyme is a member of the phosphagen (guanidino) kinase family
additional information
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the enzyme is a member of the phosphagen (guanidino) kinase family
additional information
the enzyme is a member of the phosphagen kinase superfamily of enzymes
additional information
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the enzyme is a member of the phosphagen (guanidino) kinase family
additional information
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the enzyme is a member of the phosphagen (guanidino) kinase family
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ATP + creatine = ADP + phosphocreatine
ATP + creatine = ADP + phosphocreatine
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ATP + creatine = ADP + phosphocreatine
mechanism
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ATP + creatine = ADP + phosphocreatine
N-ethylglycocyamine can also act as acceptor
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ATP + creatine = ADP + phosphocreatine
kinetic model of reaction
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
mitochondrial enzymes, mechanism, overview
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ATP + creatine = ADP + phosphocreatine
enzyme is functionally coupled to ouabain-inhibited (Na+,K+)-ATPase
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ATP + creatine = ADP + phosphocreatine
bireactant catalytic mechanism, transition state stabilization by six arginines clustered in the active site of the enzyme
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ATP + creatine = ADP + phosphocreatine
catalytic cysteine, active site residues are Glu226, Glu227, and Asp228, the enzyme follows a random or an ordered bimolecular mechanism dependent on pH, direct phosphoryl transfer, no phosphorylated intermediate, overview
ATP + creatine = ADP + phosphocreatine
catalytic cysteine, active site structure involving His66 and Asp326, overview, the enzyme follows a random or an ordered bimolecular mechanism dependent on pH, direct phosphoryl transfer, no phosphorylated intermediate, overview
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ATP + creatine = ADP + phosphocreatine
catalytic cysteine, the enzyme follows a random or an ordered bimolecular mechanism dependent on pH, direct phosphoryl transfer, no phosphorylated intermediate, overview
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ATP + creatine = ADP + phosphocreatine
catalytic cysteine, the enzyme follows a random or an ordered bimolecular mechanism dependent on pH, direct phosphoryl transfer, no phosphorylated intermediate, overview
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ATP + creatine = ADP + phosphocreatine
catalytic cysteine, the enzyme follows a random or an ordered bimolecular mechanism dependent on pH, direct phosphoryl transfer, no phosphorylated intermediate, overview
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ATP + creatine = ADP + phosphocreatine
catalytic mechanism and substrate binding involving 2 flexible loops and a specificity pocket formed by Ile69 and Val325 determining substrate specificity, active site structure
ATP + creatine = ADP + phosphocreatine
random-order rapid-equilibrium mechanism
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ADP + phosphocreatine
ATP + creatine
alpha-(RP)-borano-ADP + phosphocreatine
alpha-(RP)-borano-ATP + creatine
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the SP-ADPalphaB isomer is a 70fold better substrate for creatine kinase than the RP isomer
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alpha-(SP)-borano-ADP + phosphocreatine
alpha-(SP)-borano-ATP + creatine
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the SP-ADPalphaB isomer is a 70fold better substrate for creatine kinase than the RP isomer
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ATP + creatine
ADP + creatine phosphate
ATP + creatine
ADP + phosphocreatine
ATP + cyclocreatine
ADP + phospho-cyclocreatine
ATP + glycocyamine
ADP + glycocyamine phosphate
ATP + glycocyamine
ADP + phosphoglycocyamine
ATP + N-ethylglycocyamine
ADP + N-ethylglycocyamine phosphate
dADP + phosphocreatine
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additional information
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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synergistic substrate binding, mitochondrial isoform sMiCK
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ADP + phosphocreatine
ATP + creatine
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synergistic substrate binding, muscle-type isoform MCK
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ADP + phosphocreatine
ATP + creatine
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
in the reverse direction ADP can be replaced by IDP with 18% efficiency, ADP cannot be replaced by GDP, CDP, UDP, dTDP
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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642382, 642394, 642397, 642398, 642399, 642402, 642406, 642407, 672307, 674788, 702414, 704042, 704051 -
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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creatine cannot be replaced by creatinine
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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Mg-complexes of ATP and ADP are the true substrates for the mitochondrial enzymes
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
trout
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ATP required as MgATP2-
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ATP + creatine
ADP + creatine phosphate
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ATP + creatine
ADP + phosphocreatine
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ATP + creatine
ADP + phosphocreatine
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ATP + creatine
ADP + phosphocreatine
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physiological roles: 1. buffering of ADP/ATP ratio, 2. transport of high-energy phosphates from sites of ATP production to sites of ATP consumption
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ATP + creatine
ADP + phosphocreatine
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key enzyme in energy homeostasis
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ATP + creatine
ADP + phosphocreatine
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ATP + creatine
ADP + phosphocreatine
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the enzyme is involved in energy homeostasis
2.7.3.2 creatine kinase
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