EC Number |
Inhibitors |
Structure |
---|
2.6.1.5 | Canaline |
probably acts reacting with the cofactor |
|
2.6.1.5 | 4-methylsulfonyl-2,5,6,2',4'-pentachlorobiphenyl |
significant reduction of dexamethasone-induced activity, 50% inhibition at 0.0007 mM |
|
2.6.1.5 | 4-methylsulfonyl-2,5,6,2',4',5'-hexachlorobiphenyl |
significant reduction of dexamethasone-induced activity, 50% inhibition at 0.0008 mM |
|
2.6.1.5 | ketoconazole |
significant reduction of dexamethasone-induced activity, 50% inhibition at 0.0011 mM |
|
2.6.1.5 | tolylfluanid |
significant reduction of dexamethasone-induced activity, 50% inhibition at 0.0014 mM |
|
2.6.1.5 | 3,4-Dihydroxyphenyllactate |
strong inhibition of all the three TAT isoenzymes |
|
2.6.1.5 | 2-oxoglutarate |
substrate inhibition at high concentration |
|
2.6.1.5 | Urea |
the enzyme shows a gradual decrease in the activity till 2.5 M urea, after which the complete loss of activity is measured |
|
2.6.1.5 | D-Aspartate |
weak inhibition |
|
2.6.1.5 | alpha-Methyl-L-aspartate |
with L-tyrosine and 2-oxoglutarate or oxaloacetate as substrates |
|