Ligand 2-oxoglutaric acid

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Basic Ligand Information

Molecular Structure

C₅H₆O₅

2-oxoglutaric acid

KPGXRSRHYNQIFN-UHFFFAOYSA-N

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Synonyms:

2-Ketoglutarate, 2-ketoglutaric acid, 2-oxo-1,5-pentandioate, 2-oxo-1,5-pentanedioate, 2-oxo-glutarate, 2-oxoglutamate, 2-oxoglutarate, 2-oxoglutarate (charged), 2-oxogutarate, 2-oxopentanedioate, 2-oxopentanedioic acid, 2-[3,3,4,4-(2)H(4)]ketoglutarate, alpha-keto-glutarate, alpha-ketoglutarate, alpha-Ketoglutaric acid, alpha ketoglutarate, ketoglutarate, L-2-oxoglutarate, oxoglutarate

Related pathways

BRENDA

(5R)-carbapenem carboxylate biosynthesis, (S)-reticuline biosynthesis, alanine metabolism, arginine metabolism, aspartate and asparagine metabolism

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KEGG

2-Oxocarboxylic acid metabolism, Alanine, aspartate and glutamate metabolism, Arginine biosynthesis, Ascorbate and aldarate metabolism, Bile secretion

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MetaCyc

(-)-4'-demethyl-epipodophyllotoxin biosynthesis, (2-trimethylamino)ethylphosphonate degradation, (3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis, (5R)-carbapenem carboxylate biosynthesis, (Kdo)2-lipid A biosynthesis (P. putida), (R)-cysteate degradation, (S)-reticuline biosynthesis I, (S)-reticuline biosynthesis II, 12-epi-fischerindole biosynthesis, 12-epi-hapalindole biosynthesis, 2'-deoxymugineic acid phytosiderophore biosynthesis, 2,4-dichlorophenoxyacetate degradation, 2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol biosynthesis, 2-aminoethylphosphonate degradation III, 2-carboxy-1,4-naphthoquinol biosynthesis, 2-oxoglutarate decarboxylation to succinyl-CoA, 3-(4-hydroxyphenyl)pyruvate biosynthesis, 3-(imidazol-5-yl)lactate salvage, 3-hydroxy-4-methyl-proline biosynthesis, 3-hydroxy-L-homotyrosine biosynthesis, 3-hydroxyquinaldate biosynthesis, 3-methyl-branched fatty acid alpha-oxidation, 3-methylarginine biosynthesis, 3-[(E)-2-isocyanoethenyl]-1H-indole biosynthesis, 4-aminobutanoate degradation I, 4-aminobutanoate degradation II, 4-aminobutanoate degradation III, 4-aminobutanoate degradation V, 4-chloro-2-methylphenoxyacetate degradation, 4-hydroxybenzoate biosynthesis I (eukaryotes), 5-hydroxymethylfurfural degradation, 6-methoxypodophyllotoxin biosynthesis, 8-O-methylated benzoxazinoid glucoside biosynthesis, achromobactin biosynthesis, alpha-tomatine biosynthesis, ammonia assimilation cycle I, ammonia assimilation cycle II, ammonia assimilation cycle III, anaerobic energy metabolism (invertebrates, cytosol), anditomin biosynthesis, anteiso-branched-chain fatty acid biosynthesis, anthocyanin biosynthesis, anthocyanin biosynthesis (delphinidin 3-O-glucoside), anthocyanin biosynthesis (pelargonidin 3-O-glucoside), apigeninidin 5-O-glucoside biosynthesis, atromentin biosynthesis, baumannoferrin biosynthesis, beta-alanine degradation I, beta-alanine degradation III, brassicicene C biosynthesis, C4 photosynthetic carbon assimilation cycle, NAD-ME type, C4 photosynthetic carbon assimilation cycle, PEPCK type, chloramphenicol biosynthesis, chrysin biosynthesis, clavulanate biosynthesis, CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis, CMP-diacetamido-8-epilegionaminic acid biosynthesis, CMP-legionaminate biosynthesis I, CMP-pseudaminate biosynthesis, coenzyme B biosynthesis, coenzyme M biosynthesis II, coumarins biosynthesis (engineered), curacin A biosynthesis, cylindrospermopsin biosynthesis, cytosolic NADPH production (yeast), D-arabinose degradation III, D-cycloserine biosynthesis, D-galactarate degradation II, D-galacturonate degradation II, D-glucarate degradation II, D-glucuronate degradation II, D-phenylglycine degradation, D-xylose degradation III, D-xylose degradation V, dapdiamides biosynthesis, deacetylcephalosporin C biosynthesis, dehydrophos biosynthesis, DIMBOA-glucoside biosynthesis, domoic acid biosynthesis, dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis, dTDP-3-acetamido-alpha-D-fucose biosynthesis, dTDP-alpha-D-forosamine biosynthesis, dTDP-alpha-D-mycaminose biosynthesis, dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis, dTDP-beta-L-4-epi-vancosamine biosynthesis, dTDP-beta-L-megosamine biosynthesis, dTDP-D-desosamine biosynthesis, dTDP-L-daunosamine biosynthesis, dTDP-N-acetylthomosamine biosynthesis, dTDP-N-acetylviosamine biosynthesis, dTDP-sibirosamine biosynthesis, ectoine biosynthesis, ectoine degradation, ephedrine biosynthesis, esculetin biosynthesis, ethene biosynthesis II (microbes), ethene biosynthesis IV (engineered), ethene biosynthesis V (engineered), even iso-branched-chain fatty acid biosynthesis, FeMo cofactor biosynthesis, flavonoid biosynthesis, flavonoid biosynthesis (in equisetum), flavonol biosynthesis, FR-900098 and FR-33289 antibiotics biosynthesis, fumitremorgin A biosynthesis, furfural degradation, fusicoccin A biosynthesis, GABA shunt I, GABA shunt II, gamma-butyrobetaine degradation II, GDP-D-perosamine biosynthesis, GDP-L-colitose biosynthesis, GDP-N-acetyl-alpha-D-perosamine biosynthesis, GDP-N-formyl-alpha-D-perosamine biosynthesis, gentamicin biosynthesis, gibberellin biosynthesis I (non C-3, non C-13 hydroxylation), gibberellin biosynthesis II (early C-3 hydroxylation), gibberellin biosynthesis III (early C-13 hydroxylation), gibberellin biosynthesis V, gibberellin inactivation I (2beta-hydroxylation), glutarate degradation, guadinomine B biosynthesis, hapalindole H biosynthesis, hectochlorin biosynthesis, homotaurine degradation, hopanoid biosynthesis (bacteria), hydroxylated mugineic acid phytosiderophore biosynthesis, hygromycin B biosynthesis, ibotenate and muscimol biosynthesis, incomplete reductive TCA cycle, indole-3-acetate biosynthesis II, indole-3-acetate biosynthesis VI (bacteria), isoflavonoid biosynthesis II, kainate biosynthesis, kanamycin biosynthesis, kanosamine biosynthesis II, L-alanine biosynthesis I, L-alanine biosynthesis II, L-alanine degradation II (to D-lactate), L-alanine degradation III, L-alanine degradation V (oxidative Stickland reaction), L-alanine degradation VI (reductive Stickland reaction), L-arabinose degradation III, L-arginine biosynthesis II (acetyl cycle), L-arginine biosynthesis III (via N-acetyl-L-citrulline), L-arginine biosynthesis IV (archaea), L-arginine degradation I (arginase pathway), L-arginine degradation II (AST pathway), L-arginine degradation VI (arginase 2 pathway), L-arginine degradation XI, L-arginine degradation XIII (reductive Stickland reaction), L-asparagine degradation III (mammalian), L-aspartate biosynthesis, L-aspartate degradation I, L-carnitine biosynthesis, L-citrulline biosynthesis, L-cysteine biosynthesis IX (Trichomonas vaginalis), L-cysteine degradation I, L-cysteine degradation III, L-dopa degradation I (mammalian), L-glutamate biosynthesis I, L-glutamate biosynthesis II, L-glutamate biosynthesis III, L-glutamate biosynthesis IV, L-glutamate biosynthesis V, L-glutamate degradation I, L-glutamate degradation II, L-glutamate degradation V (via hydroxyglutarate), L-glutamate degradation X, L-glutamate degradation XI (reductive Stickland reaction), L-glutamine degradation II, L-histidine biosynthesis, L-histidine degradation IV, L-histidine degradation VI, L-isoleucine biosynthesis I (from threonine), L-isoleucine biosynthesis II, L-isoleucine biosynthesis III, L-isoleucine biosynthesis IV, L-isoleucine biosynthesis V, L-isoleucine degradation I, L-isoleucine degradation II, L-isoleucine degradation III (oxidative Stickland reaction), L-leucine biosynthesis, L-leucine degradation I, L-leucine degradation II, L-leucine degradation III, L-leucine degradation IV (reductive Stickland reaction), L-leucine degradation V (oxidative Stickland reaction), L-lysine biosynthesis I, L-lysine biosynthesis II, L-lysine biosynthesis IV, L-lysine biosynthesis V, L-lysine biosynthesis VI, L-lysine degradation I, L-lysine degradation II (L-pipecolate pathway), L-lysine degradation III, L-lysine degradation IV, L-lysine degradation V, L-lysine degradation VI, L-lysine degradation X, L-lysine degradation XI, L-lyxonate degradation, L-Ndelta-acetylornithine biosynthesis, L-ornithine biosynthesis I, L-ornithine biosynthesis II, L-phenylalanine biosynthesis I, L-phenylalanine biosynthesis II, L-phenylalanine degradation II (anaerobic), L-phenylalanine degradation III, L-phenylalanine degradation IV (mammalian, via side chain), L-phenylalanine degradation VI (reductive Stickland reaction), L-proline biosynthesis III (from L-ornithine), L-proline biosynthesis IV, L-serine biosynthesis I, L-tryptophan degradation IV (via indole-3-lactate), L-tryptophan degradation VIII (to tryptophol), L-tryptophan degradation XI (mammalian, via kynurenine), L-tryptophan degradation XIII (reductive Stickland reaction), L-tyrosine biosynthesis I, L-tyrosine biosynthesis II, L-tyrosine biosynthesis III, L-tyrosine degradation I, L-tyrosine degradation II, L-tyrosine degradation III, L-tyrosine degradation IV (to 4-methylphenol), L-tyrosine degradation V (reductive Stickland reaction), L-valine biosynthesis, L-valine degradation I, L-valine degradation II, L-valine degradation III (oxidative Stickland reaction), leucodelphinidin biosynthesis, leucopelargonidin and leucocyanidin biosynthesis, luteolin biosynthesis, luteolinidin 5-O-glucoside biosynthesis, malate/L-aspartate shuttle pathway, mannojirimycin biosynthesis, methylaspartate cycle, methylphosphonate degradation III, mixed acid fermentation, morphine biosynthesis, myxochelin A and B biosynthesis, N-hydroxy-L-pipecolate biosynthesis, neomycin biosynthesis, neopentalenoketolactone and pentalenate biosynthesis, nevadensin biosynthesis, nicotine degradation I (pyridine pathway), nitrogen remobilization from senescing leaves, nopaline degradation, norspermidine biosynthesis, nylon-6 oligomer degradation, odd iso-branched-chain fatty acid biosynthesis, ophthalmate biosynthesis, paerucumarin biosynthesis, paromomycin biosynthesis, partial TCA cycle (obligate autotrophs), pentalenolactone biosynthesis, photorespiration I, photorespiration II, photorespiration III, pinobanksin biosynthesis, platensimycin biosynthesis, polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium), polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium), polymyxin resistance, proanthocyanidins biosynthesis from flavanols, procollagen hydroxylation and glycosylation, putrescine degradation I, pyoverdine I biosynthesis, pyridoxal 5'-phosphate biosynthesis I, quinolinone B biosynthesis, reductive TCA cycle I, reductive TCA cycle II, rhabduscin biosynthesis, rhizobactin 1021 biosynthesis, ribostamycin biosynthesis, roseoflavin biosynthesis, rosmarinic acid biosynthesis I, rosmarinic acid biosynthesis II, rutin biosynthesis, S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I, scopoletin biosynthesis, septacidin biosynthesis, solasodine and soladulcidine biosynthesis, staphyloferrin B biosynthesis, stipitatate biosynthesis, sulfazecin biosynthesis, sulfolactate degradation III, superpathway of hyoscyamine (atropine) and scopolamine biosynthesis, superpathway of scopolin and esculin biosynthesis, syringetin biosynthesis, taurine degradation III, taurine degradation IV, TCA cycle I (prokaryotic), TCA cycle II (plants and fungi), TCA cycle III (animals), TCA cycle IV (2-oxoglutarate decarboxylase), TCA cycle V (2-oxoglutarate synthase), TCA cycle VI (Helicobacter), TCA cycle VII (acetate-producers), TCA cycle VIII (Chlamydia), trans-4-hydroxy-L-proline degradation I, trans-4-hydroxy-L-proline degradation II, tropane alkaloids biosynthesis, UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate biosynthesis, UDP-3-acetamido-2-amino-2,3-dideoxy-alpha-D-glucopyranose biosynthesis, UDP-N,N'-diacetylbacillosamine biosynthesis, UDP-yelosamine biosynthesis, umbelliferone biosynthesis, validamycin biosynthesis, vindoline, vindorosine and vinblastine biosynthesis, viridicatin biosynthesis, zwittermicin A biosynthesis

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