EC Number |
Activating Compound |
Reference |
---|
6.1.1.6 | AMP |
stimulation of diadenosine 5',5'''-P1,P4-tetraphosphate synthetase activity |
500 |
6.1.1.6 | aspartyl-tRNA synthetase |
EC 6.1.1.12, AspRS, from the multi-synthetase complex. HKRS and hKRSDELTA60 are differentially stimulated by |
690704 |
6.1.1.6 | Diphosphatase |
- |
674885 |
6.1.1.6 | Diphosphatase |
stimulation of diadenosine 5',5'''-P1,P4-tetraphosphate synthetase activity |
500 |
6.1.1.6 | dithiothreitol |
activates 30fold the aminoacylation raection |
649906 |
6.1.1.6 | epidermal growth factor receptor |
activation of LysRS by epidermal growth factor receptor (EGFR) |
745950 |
6.1.1.6 | more |
specific binding to HIV Gag protein, thereby signaling and mediation of selective recognition and packaging of tRNALys isoacceptors as well as the enzyme itself into HIV particles, the Gag protein alone is sufficient for the incorporation, determination and mapping of interaction regions |
652421 |
6.1.1.6 | more |
the non-synthetase protein from the multi-synthetase complex p38 alone does not affect hKRS lysylation but inhibited the AspRS-mediated stimulation of hKRS |
690704 |
6.1.1.6 | syntenin-1 |
tandem PDZ protein, regulates KRS activity, adaptor modulating the activity of KRS. A point mutation in the PDZ2 domain of syntenin-1 abrogates interaction with KRS |
693871 |
6.1.1.6 | translation elongation factor 1alpha |
EF1alpha, hKRSDELTA60 binds to EF1alpha and is stimulated by EF1alpha in vitro |
690704 |