Activating Compound | Comment | Organism | Structure |
---|---|---|---|
aspartyl-tRNA synthetase | EC 6.1.1.12, AspRS, from the multi-synthetase complex. HKRS and hKRSDELTA60 are differentially stimulated by | Homo sapiens | |
additional information | the non-synthetase protein from the multi-synthetase complex p38 alone does not affect hKRS lysylation but inhibited the AspRS-mediated stimulation of hKRS | Homo sapiens | |
translation elongation factor 1alpha | EF1alpha, hKRSDELTA60 binds to EF1alpha and is stimulated by EF1alpha in vitro | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
hKRSDELTA1-24 | deletion mutation. Construct shows significant stimulation of lysylation by EF1alpha and binding to EF1alpha | Homo sapiens |
hKRSDELTA24-42 | deletion mutation. Construct shows significant stimulation of lysylation by EF1alpha and binding to EF1alpha | Homo sapiens |
hKRSDELTA60 | removal of the amino-terminal extension | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q15046 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
hKRS | - |
Homo sapiens |
Lysyl-tRNA synthetase | interacts with EF1alpha, aspartyl-tRNA synthetase (EC 6.1.1.12) and p38 in vitro | Homo sapiens |