EC Number   |
Activating Compound |
Reference |
|---|
   3.4.25.1 | Rpt2 |
the 19S ATPase subunits, Rpt2 and Rpt5, bind ATP, their C-termini dock into intersubunit pockets in the 20S particle alpha-ring and induce gate opening, activating the protease activity. A conserved HbYX motif in the C-terminus is required |
719367 |
| 3.4.25.1 | Rpt5 |
the 19S ATPase subunits, Rpt2 and Rpt5, bind ATP, their C-termini dock into intersubunit pockets in the 20S particle alpha-ring and induce gate opening, activating the protease activity. A conserved HbYX motif in the C-terminus is required |
719367 |
| 3.4.25.1 | SDS |
increased activity in the presence of 0.02% SDS |
689978 |
| 3.4.25.1 | SDS |
significantly stimulates activity of the 20S proteasome at pH 7.5, completely inhibits at pH 5.5 |
670038 |
| 3.4.25.1 | SDS |
stimulates chymotrypsin-like activity |
137329 |
| 3.4.25.1 | SDS |
stimulates chymotrypsin-like activity and Staphylococcus aureus V8 like activity |
137335 |
| 3.4.25.1 | SDS |
stimulates chymotrypsin-like activity, hydrolysis of benzyloxycarbonyl-GGL-4-nitroanilide and peptidyl-glutamyl-peptide-hydrolyzing activity, hydrolysis of benzyloxycarbonyl-LLE-2-naphthylamide |
649428 |
| 3.4.25.1 | SDS |
stimulates peptidylglutamyl peptide hydrolase, branched-chain amino acid preferring and caseinolytic activities |
137332 |
