3.4.25.1	19S regulatory complex	represents the major proteasome activator	712918	
3.4.25.1	19S regulatory particle	-	688337	
3.4.25.1	3H-1,2-dithiole-3-thione	tissue specific increase of the catalytic subunits of the proteasome following oral administration of 0.5 mmol/kg	688760	
3.4.25.1	aflatoxin G1	specific stimulator of activity	685443	
3.4.25.1	Blm10 protein	-	688337	
3.4.25.1	chymostatin	0.05 mg/ml, activation to 170% of the original activity, peptidyl-glutamyl-peptide-hydrolyzing activity, hydrolysis of benzyloxycarbonyl-LLE-2-naphthylamide	649428	
3.4.25.1	doxorubicin	apoptosis inductor doxorubicin increases enzymatic activities, regulates subunit composition, and phosphorylation state of 26S proteasomes	685994	
3.4.25.1	histone H3	slective activation of the branched-chain amino acid preferring activity with benzyloxycarbonyl-GPALG-4-aminobenzoate as substrate, 1000%	650040	
3.4.25.1	KYFTGSKLWRSYYA	peptidic activator, based on the Blm10 activator of 20S proteasome. At 10 microM concentration, chymotrypsin-like and peptidylglutamyl peptide hydrolyzing activities increase around three times whereas trypsin-like activity increases around 7fold	755477	
3.4.25.1	leupeptin	0.05 mg/ml, activation to 125% of the original activity, peptidyl-glutamyl-peptide-hydrolyzing activity, hydrolysis of benzyloxycarbonyl-LLE-2-naphthylamide	649428	
3.4.25.1	additional information	immediate early gene-X-1 may essentially modulate signalling pathways related to 26S proteasome activity	684965	
3.4.25.1	additional information	occupancy of the caspase-like sites stimulates the trypsin-like activity of the proteasomes	652508	
3.4.25.1	nuclear factor erythroid-derived 2-related factor 1	i.e. Nrf1, a transcription factor of the cap and collar basic leucine zipper family, but not the related Nrf2, is necessary for induced proteasome gene transcription in cancer cell lines, overview	713032	
3.4.25.1	nuclear factor erythroid-derived 2-related factor 1	i.e. Nrf1, a transcription factor of the cap and collar basic leucine zipper family, but not the related Nrf2, is necessary for induced proteasome gene transcription in mouse embryonic fibroblasts, overview. Knockdown of Nrf1 in wild-type mouse embryonic fibroblasts abolishes MG132-mediated upregulation of RNA levels of PSM genes	713032	
3.4.25.1	PA200	activator protein	752830	
3.4.25.1	PA28	activator protein	752830	
3.4.25.1	PA28	protein activator	137336	
3.4.25.1	poly-L-lysine	stimulates chymotrypsin-, trypsin- and Staphylococcus aureus V8-like activities	137335	
3.4.25.1	polylysine	stimulates caseinolytic activity	649428	
3.4.25.1	protein kinase A	protein kinase A treatment drastically enhances 20S peptidase activities in a dose-dependent fashion	686124	
3.4.25.1	Rpt2	the 19S ATPase subunits, Rpt2 and Rpt5, bind ATP, their C-termini dock into intersubunit pockets in the 20S particle alpha-ring and induce gate opening, activating the protease activity. A conserved HbYX motif in the C-terminus is required	719367	
3.4.25.1	Rpt5	the 19S ATPase subunits, Rpt2 and Rpt5, bind ATP, their C-termini dock into intersubunit pockets in the 20S particle alpha-ring and induce gate opening, activating the protease activity. A conserved HbYX motif in the C-terminus is required	719367	
3.4.25.1	SDS	increased activity in the presence of 0.02% SDS	689978	
3.4.25.1	SDS	significantly stimulates activity of the 20S proteasome at pH 7.5, completely inhibits at pH 5.5	670038	
3.4.25.1	SDS	stimulates chymotrypsin-like activity	137329	
3.4.25.1	SDS	stimulates chymotrypsin-like activity and Staphylococcus aureus V8 like activity	137335	
3.4.25.1	SDS	stimulates chymotrypsin-like activity, hydrolysis of benzyloxycarbonyl-GGL-4-nitroanilide and peptidyl-glutamyl-peptide-hydrolyzing activity, hydrolysis of benzyloxycarbonyl-LLE-2-naphthylamide	649428	
3.4.25.1	SDS	stimulates peptidylglutamyl peptide hydrolase, branched-chain amino acid preferring and caseinolytic activities	137332