Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

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Localization

Enzyme

Details for alkylbase DNA N-glycosylase activity

3.2.2.21

Gene ontology ID

GO:0003905

Definition

Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site

Synonyms

1. 3-methyladenine DNA glycosylase II
2. AlkA
3. alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
4. alkylbase DNA glycosidase activity
5. deoxyribonucleate 3-methyladenine glycosidase II
6. DNA glycosidase II activity
7. DNA-3-methyladenine glycosidase II activity
8. DNA-3-methyladenine glycosylase II

References

1. EC 3.2.2.21
2. GOC: elh
3. PMID 10872450
4. PMID 9224623
5. MetaCyc 3.2.2.21-RXN

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

molecular_function is a

catalytic activity is a

catalytic activity, acting on DNA is a

DNA N-glycosylase activity is a

alkylbase DNA N-glycosylase activity is a

oxidized base lesion DNA N-glycosylase activity is a

Tree view

Gene ontology

biological_process is a

cellular_component is a

molecular_function is a

binding

catalytic activity is a

catalytic activity, acting on a protein is a

catalytic activity, acting on DNA is a

5'-deoxyribose-5-phosphate lyase activity is a

deoxyribodipyrimidine endonucleosidase activity is a

DNA alpha-glucosyltransferase activity is a

DNA beta-glucosyltransferase activity is a

DNA N-glycosylase activity is a

alkylbase DNA N-glycosylase activity is a

deaminated base DNA N-glycosylase activity is a

mismatch base pair DNA N-glycosylase activity is a

oxidized base lesion DNA N-glycosylase activity is a

oxidized purine nucleobase lesion DNA N-glycosylase activity is a

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity is a

pyrimidine dimer DNA N-glycosylase activity is a

DNA nucleotidylexotransferase activity is a

DNA photolyase activity is a

DNA-(apurinic or apyrimidinic site) endonuclease activity is a

DNA-deoxyinosine glycosylase activity is a

DNA/RNA helicase activity is a

phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands is a

transposase activity is a

tyrosyl-DNA phosphodiesterase activity is a

catalytic activity, acting on RNA is a

cyclase activity is a

hydrolase activity is a

isomerase activity is a

ligase activity is a

lyase activity is a

peptidoglycan muralytic activity is a

transferase activity is a

molecular transducer activity is a

nutrient reservoir activity is a

protein tag is a

small molecule sensor activity is a

structural molecule activity is a

transcription regulator activity is a

transporter activity is a