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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for NAD-dependent histone deacetylase activity (H3-K9 specific)
3.5.1.17
Gene ontology ID
GO:0046969
Definition
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein
References
1. EC 3.5.1.17
2. RHEA: 24548
3. Reactome: R-HSA-9604829 "SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters"
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