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Gene ontology
Version 2014-12-22
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Details for tissue kallikrein-kinin cascade
Gene ontology ID
GO:0002255
Definition
A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability
Synonyms
1. glandular kallikrein-kinin cascade
References
1. GOC: add
2. PMID 11842287
3. PMID 14501145
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