show all | hide all No of entries

Information on EC 4.2.1.130 - D-lactate dehydratase

for references in articles please use BRENDA:EC4.2.1.130
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.130 D-lactate dehydratase
IUBMB Comments
The enzyme, described from the fungi Candida albicans and Schizosaccharomyces pombe, converts 2-oxopropanal to (R)-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalysed by EC 4.4.1.5 (lactoylglutathione lyase) and EC 3.1.2.6 (hydroxyacylglutathione hydrolase).
Specify your search results
Select one or more organisms in this record: ?
Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
hsp31, glyoxalase iii, dj-1a, dj-1b, glutathione-independent glyoxalase, hsp3101, hsp3102, glutathione-independent glyoxalase iii, dj-1 glyoxalase, hsp31p glyoxalase iii, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-lactate = 2-oxopropanal + H2O
show the reaction diagram
Select items on the left to see more content.