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Information on EC 4.2.1.116 - 3-hydroxypropionyl-CoA dehydratase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.116 3-hydroxypropionyl-CoA dehydratase
IUBMB Comments
Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea . The enzyme from Metallosphaera sedula acts nearly equally as well on (S)-3-hydroxybutanoyl-CoA but not (R)-3-hydroxybutanoyl-CoA .
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
3-hydroxypropionyl-CoA dehydratase, 3-hydroxypropionyl-coenzyme A dehydratase, 3HPCD, HPCD, Ms3HPCD, Msed_2001, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O
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