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Information on EC 3.4.19.14 - leukotriene-C4 hydrolase

for references in articles please use BRENDA:EC3.4.19.14

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IUBMB Comments

The mouse enzyme is specific for leukotriene C4, while the human enzyme also has considerable activity towards glutathione and oxidized glutathione (cf. EC 3.4.19.13, glutathione hydrolase) [3-4].

The enzyme appears in viruses and cellular organisms

Synonyms
gamma-glutamyl leukotrienase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
leukotriene C4 + H2O = leukotriene D4 + L-glutamate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links