Ligand leukotriene C4

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Basic Ligand Information

Molecular Structure
Picture of leukotriene C4 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H47N3O9S
leukotriene C4
GWNVDXQDILPJIG-NXOLIXFESA-N
Synonyms:
cysteinyl leukotriene LTC4, leukotriene C


Show all pahtways known for Show all BRENDA pathways known for leukotriene C4

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
leukotriene C4 = leukotriene A4 + glutathione
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
leukotriene A4 + glutathione = leukotriene C4
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
leukotriene C4 + ascorbate + O2 = ? + dehydroascorbate + H2O
show the reaction diagram
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leukotriene C4 + H2O = ?
show the reaction diagram
-
leukotriene C4 + H2O = leukotriene D4 + L-glutamate
show the reaction diagram
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leukotriene C4 = leukotriene A4 + glutathione
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glutathione + leukotriene D = cysteinylglycine + leukotriene C
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (14 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.035
-
pH 6.0, 37°C

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0021
-
IC50: 0.0021 mM, inhibits reaction with leukotriene C4 methyl ester
0.0012
-
-

References & Links

Links to other databases for leukotriene C4

ChEBI
PubChem
ChEBI
PubChem