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Literature summary for 3.4.19.14 extracted from
- gamma-Glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen (1998), J. Biol. Chem., 273, 28277-28285.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in NIH/3T3 cells | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q9Z2A9 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | the enzyme has six putative N-glycosylation sites | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
| bronchiolar epithelium | - |
Mus musculus | - |
| heart | - |
Mus musculus | - |
| kidney | - |
Mus musculus | - |
| liver | - |
Mus musculus | - |
| lung | pulmonary interstitial cell | Mus musculus | - |
| lymphocyte | - |
Mus musculus | - |
| neuron | the enzyme is detected in cerebral, cerebellar, and brain stem neurons but not in glial cells | Mus musculus | - |
| renal proximal tubule | - |
Mus musculus | - |
| small intestine | crypt cells of the small intestine | Mus musculus | - |
| spleen | the enzyme is primarily expressed in spleen | Mus musculus | - |
| thymus | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene C4 + H2O | - |
Mus musculus | leukotriene D4 + L-glutamate | - |
? |  |
| additional information | no activity with GSH or gamma-glutamyl-4-nitroanilide | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gamma-glutamyl leukotrienase | - |
Mus musculus |
| GGL | - |
Mus musculus |
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