Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 2.7.1.169 - pantoate kinase

for references in articles please use BRENDA:EC2.7.1.169

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The conversion of (R)-pantoate to (R)-4′-phosphopantothenate is part of the pathway leading to biosynthesis of 4′-phosphopantetheine, an essential cofactor of coenzyme A and acyl-carrier protein. In bacteria and eukaryotes this conversion is performed by condensation with β-alanine, followed by phosphorylation (EC 6.3.2.1 and EC 2.7.1.33, respectively). In archaea the order of these two steps is reversed, and phosphorylation precedes condensation with β-alanine.

The expected taxonomic range for this enzyme is: Archaea, Bacteria

Synonyms
pantoate kinase, mhun_0831, cog1829, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + (R)-pantoate = ADP + (R)-4-phosphopantoate
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
phosphopantothenate biosynthesis III (archaea)
Highest Expressing Human Cell Lines
Cell Line Links Gene Links