Ligand (R)-pantoate

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Basic Ligand Information

Molecular Structure
Picture of (R)-pantoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12O4
(R)-pantoate
OTOIIPJYVQJATP-BYPYZUCNSA-N
Synonyms:
D-pantoate, D-pantoic acid


Show all pahtways known for Show all BRENDA pathways known for (R)-pantoate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH
show the reaction diagram
-
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (36 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH
show the reaction diagram
-
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-pantolactone + H2O = D-pantoic acid
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
noncompetitive with ketopantoic acid at saturation level of NADPH, noncompetitive with NADPH at unsaturation level of ketopantoic acid

3D Structure of Enzyme-Ligand-Complex (PDB) (6 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.033
-
at pH 10.0

References & Links

Links to other databases for (R)-pantoate

ChEBI
PubChem
ChEBI
PubChem