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Information on EC 2.4.1.347 - alpha,alpha-trehalose-phosphate synthase (ADP-forming)

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IUBMB Comments
The enzyme has been reported from the yeast Saccharomyces cerevisiae and from mycobacteria. The enzyme from Mycobacterium tuberculosis can also use UDP-alpha-D-glucose, but the activity with ADP-alpha-D-glucose, which is considered the main substrate in vivo, is higher.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
adenosine-5'-diphosphoglucose-dependent trehalose synthase, ADP-glucose-glucose-phosphate glucosyltransferase, ADPG-dependent trehalose synthase, OtsA, TPS, Tre-6P Sase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ADP-alpha-D-glucose + D-glucose 6-phosphate = ADP + alpha,alpha-trehalose 6-phosphate
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