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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.4.1.347metabolism the enzyme is responsible for maltose-induced trehalose accumulation probably by forming a complex with a specific trehalose-6-phosphatase activity 741948
Display the reaction diagram Show all sequences 2.4.1.347physiological function the OtsA-OtsB2 pathway involves trehalose 6-phosphate synthase OtsA and trehalose 6-phosphate phosphatase OtsB2. OtsA is dispensable, but OtsB2 is strictly essential for growth of Mycobaceterium tuberculosis. Essentiality of OtsB2 is linked to accumulation of its substrate trehalose 6-phosphate, which exhibits direct or indirect toxic effects -, 760053
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