pivotal enzyme controlling the metabolic flow of lysophosphatidic acid into different phosphatidic acids in diverse tissues, enzyme is essential in embryo development
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
the enzyme shows a preference for acylating long-chain fatty acids. Substrate specificity is evaluated with 18:1- or 22:6-LPA, and 18:3-, 20:5-, 22:5-, 22:6-CoAs. Mortierella alpina LPAAT has the highest substrate specificity for accumulating DHA onto oleoyl-lysophosphatidic acid (oleoyl-LPA), while the plant LPAATs tested show lower preference for docosahexaenoic acid (DHA). Competition among acyl donor substrates for LPAATs, overview
pivotal enzyme controlling the metabolic flow of lysophosphatidic acid into different phosphatidic acids in diverse tissues, enzyme is essential in embryo development
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum
comparison of the substrate specificities of enzymes from different species, positional analysis of fatty acids in seed oil and tiacylglycerols, overview
LPAAT is a crucial enzyme controlling the metabolic flow of lysophosphatidic acid into the pool of phosphatidic acid, which plays a key role in many physiological aspects, such as cell signaling, cell polarity, and apoptotic signaling cascades in higher eukaryotes. Phosphatidic acid specifically regulates the genes involved in modulating cell shape and organization
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview
gene At4g24160, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression of the His-tagged enzyme in Escherichia coli strain BL21(DE3)
gene LPAT2, genetic structure, LPAT2-cDNA driven by an LPAT2 promoter functionally complements insertion mutant lpat2 in transformed heterozygous mutants to produce the lpat2/lpat2 genotype, overview, phylogenetic tree, functional expression in Saccharomyces cerevisiae, genotyping
Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis