EC Number   |
Natural Substrates |
|---|
    2.3.1.51 | acyl-CoA + 1-acyl-lysophosphatidic acid |
- |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
- |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
i.e. lysophosphatidic acid |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
involved in phospholipid biosynthesis |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
pivotal enzyme controlling the metabolic flow of lysophosphatidic acid into different phosphatidic acids in diverse tissues, enzyme is essential in embryo development |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
reduction in AGPAT2 activity underlies the loss of adipose tissue in congenital generalized lipodystrophy |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
AGPAT2 catalyzes acylation of lysophosphatidic acid to phosphatidic acid, a precursor for both triacylglycerol and phospholipid synthesis, isozyme AGPAT2 plays a regulatory role in adipocyte differentiation |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
the enzyme catalyzes the second acylations in the glycerol-3-phosphate pathway |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
the expression of AGPATs is linked to skin barrier requirements |
| 2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate |
activity and expression pattern of AGPAT9 in lung and spleen implicates role in the biosynthesis of phospholipids and triglycerides in these tissues |
