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Literature summary for 2.3.1.51 extracted from

  • Kim, H.U.; Li, Y.; Huang, A.H.
    Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis (2005), Plant Cell, 17, 1073-1089.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene LPAT1, genetic structure, phylogenetic tree Arabidopsis thaliana
gene LPAT2, genetic structure, LPAT2-cDNA driven by an LPAT2 promoter functionally complements insertion mutant lpat2 in transformed heterozygous mutants to produce the lpat2/lpat2 genotype, overview, phylogenetic tree, functional expression in Saccharomyces cerevisiae, genotyping Arabidopsis thaliana
gene LPAT3, genetic structure, phylogenetic tree, functional expression in Saccharomyces cerevisiae, genotyping Arabidopsis thaliana
gene LPAT4, genetic structure, phylogenetic tree, expression in Saccharomyces cerevisiae results in an inactive enzyme Arabidopsis thaliana
gene LPAT5, genetic structure, phylogenetic tree, expression in Saccharomyces cerevisiae results in an inactive enzyme Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information identification of a null allele lpat2 having a T-DNA inserted into LPAT2, the heterozygous mutant LPAT2/lpat2 has a minimal altered vegetative phenotype but produces shorter siliques that contain normal seeds and remnants of aborted ovules in a 1:1 ratio, overview, lpat2 causes lethality in the female gametophyte but not the male gametophyte, which has the redundant LPAT3, that complements, phenotypes, overview Arabidopsis thaliana
additional information LPAT3-cDNA functionally complements the lpat2 LPAT2 mutant strain in part in heterozygous LPAT2/lpat2 and homozygous lpat2/lpat2 mutants, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol LPAT1 Arabidopsis thaliana 5829
-
cytosol LPAT3 Arabidopsis thaliana 5829
-
cytosol LPAT4 Arabidopsis thaliana 5829
-
cytosol LPAT5 Arabidopsis thaliana 5829
-
endoplasmic reticulum LPAT2, co-localizes with calreticulin in the endoplasmic reticulum Arabidopsis thaliana 5783
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum ?
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8GXU8 LPAT1; gene LPAT1
-
Arabidopsis thaliana Q8L4Y2 LPAT4; gene LPAT4
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Arabidopsis thaliana Q8LG50 LPAT2; gene LPAT2
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Arabidopsis thaliana Q9LHN4 LPAT5; gene LPAT5
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Arabidopsis thaliana Q9SYC8 LPAT3; gene LPAT3
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Source Tissue

Source Tissue Comment Organism Textmining
callus
-
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
gametophyte the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana Arabidopsis thaliana
-
leaf
-
Arabidopsis thaliana
-
additional information LPAT2 is expressed ubiquitously in diverse tissues, tissue-specific expression levels, overview Arabidopsis thaliana
-
pollen LPAT2 predominantly Arabidopsis thaliana
-
root
-
Arabidopsis thaliana
-
silique
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the endoplasmic reticulum-located LPAT2 is essential for female but not male gametophyte development in Arabidopsis thaliana, LPAT2 co-localizes with calreticulin in the endoplasmic reticulum Arabidopsis thaliana ?
-
?

Synonyms

Synonyms Comment Organism
endoplasmic reticulum-located LPAT
-
Arabidopsis thaliana
ER-located LPAT
-
Arabidopsis thaliana
LPA acyltransferase
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Arabidopsis thaliana
LPAT
-
Arabidopsis thaliana
lysophosphatidyl acyltransferase
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Arabidopsis thaliana