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Information on EC - tetrachloroethene reductive dehalogenase

for references in articles please use BRENDA:EC1.21.99.5
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IUBMB Comments
This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons. The reaction occurs in the reverse direction. The enzyme also reduces trichloroethene to dichloroethene. Although the physiological reductant is unknown, the supply of reductant in some organisms involves menaquinol, which is reduced by molecular hydrogen via the action of EC, hydrogen:quinone oxidoreductase. The enzyme contains a corrinoid and two iron-sulfur clusters. Methylviologen can act as electron donor in vitro.
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The enzyme appears in viruses and cellular organisms
reductive dehalogenase, rdase, tetrachloroethene reductive dehalogenase, pce dehalogenase, pce reductive dehalogenase, tetrachloroethene (pce) reductive dehalogenase, tetrachloroethene dehalogenase, rdha3, pce-reductive dehalogenase, pce reductase, more
trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor
show the reaction diagram
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