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Information on EC 1.17.99.6 - epoxyqueuosine reductase

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IUBMB Comments
This enzyme catalyses the last step in the bacterial biosynthetic pathway to queuosine, the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. Two types of enzymes are known to catalyse this activity. QueG enzymes are cobalamin-dependent, while QueH enzymes contain a [4Fe-4S] metallocluster along with an adjacent coordinated iron metal.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes
queuosine34 in tRNA
+
+
=
epoxyqueuosine34 in tRNA
+
Synonyms
epoxyqueuosine reductase, oq reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
queuosine34 in tRNA + acceptor + H2O = epoxyqueuosine34 in tRNA + reduced acceptor
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PATHWAY SOURCE
PATHWAYS
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