Reference on EC 1.17.4.1 - ribonucleoside-diphosphate reductase and Organism(s) Escherichia coli and UniProt Accession P00452
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kjoller Larsen, I.; Sjöberg, B.M.; Thelander, L.
Characterization of the active site of ribonucleotide reductase of Escherichia coli, bacteriophage T4 and mammalian cells by inhibition studies with hydroxyurea analogues
Eur. J. Biochem.
125
75-81
1982
Tequatrovirus T4, Bos taurus, Escherichia coli, Mus musculus
Thelander, L.; Sjöberg, B.M.; Eriksson, S.
Ribonucleoside diphosphate reductase (Escherichia coli)
Methods Enzymol.
51
227-237
1978
Escherichia coli, Escherichia coli overproducing
Lammers, M.; Follmann, H.
The ribonucleotide reductases - a unique group of metalloenzymes essential for cell proliferation
Struct. Bonding
54
27-91
1983
Tequatrovirus T4, Tequintavirus T5, Enterobacteria phage T6, Bos taurus, Saccharomyces cerevisiae, Oryctolagus cuniculus, Escherichia coli, Homo sapiens, Mesocricetus auratus, Mus musculus, Rattus norvegicus, Tetradesmus obliquus
-
Joelson, T.; Uhlin, U.; Eklund, H.; Sjöberg, B.M.; Hahne, S.; Karlsson, M.
Crystallization and preliminary crystallographic data of ribonucleotide reductase protein B2 from Escherichia coli
J. Biol. Chem.
259
9076-9077
1984
Escherichia coli
Salowe, S.P.; Stubbe, J.
Cloning, overproduction, and purification of the B2 subunit of ribonucleoside-diphosphate reductase
J. Bacteriol.
165
363-366
1986
Escherichia coli
Sahlin, M.; Sjöberg, B.M.; Backes, G.; Loehr, T.; Sanders-Loehr, J.
Activation of the iron-containing B2 protein of ribonucleotide reductase by hydrogen peroxide
Biochem. Biophys. Res. Commun.
167
813-818
1990
Escherichia coli
Smith, S.L.; Douglas, K.T.
Stereoselective, strong inhibition of ribonucleotide reductase from E. coli by cisplatin
Biochem. Biophys. Res. Commun.
162
715-723
1989
Escherichia coli
Stubbe, J.
Ribonucleotide reductases
Adv. Enzymol. Relat. Areas Mol. Biol.
63
349-419
1990
Escherichia coli, Herpes simplex virus, Mus musculus
Holmgren, A.
Regulation of ribonucleotide reductase
Curr. Top. Cell. Regul.
19
47-76
1981
Escherichia phage T2, Tequatrovirus T4, Tequintavirus T5, Enterobacteria phage T6, Bos taurus, Oryctolagus cuniculus, Escherichia coli, Homo sapiens, Rattus norvegicus
Stubbe, J.
Ribonucleotide reductases: amazing and confusing
J. Biol. Chem.
265
5329-5332
1990
Escherichia coli
Larsson, A.; Reichard, P.
Enzymatic synthesis of deoxyribonucleotides. IX. Allosteric effects in the reduction of pyrimidine ribonucleotides by the ribonucleoside diphosphate reductase system of Escherichia coli
J. Biol. Chem.
241
2533-2539
1966
Escherichia coli
Thelander, L.
Physicochemical characterization of ribonucleoside diphosphate reductase from Escherichia coli
J. Biol. Chem.
248
4591-4601
1973
Escherichia coli
Nordlund, P.; Sjöberg, B.M.; Eklund, H.
Three-dimensional structure of the free radical protein of ribonucleotide reductase
Nature
345
593-598
1990
Escherichia coli
Nordlund, P.; Uhlin, U.; Westergren, C.; Joelsen, T.; Sjöberg, B.M.; Eklund, H.
New crystal forms of the small subunit of ribonucleotide reductase from Escherichia coli
FEBS Lett.
258
251-254
1989
Escherichia coli
Ribi, H.O.; Reichard, P.; Kornberg, R.D.
Two-dimensional crystals of enzyme-effector complexes: ribonucleotide reductase at 18-A resolution
Biochemistry
26
7974-7979
1987
Escherichia coli
Bunker, G.; Petersson, L.; Sjöberg, B.M.; Sahlin, M.; Chance, M.; Chance, B.; Ehrenberg, A.
Extended X-ray absorption fine structure studies on the iron-containing subunit of ribonucleotide reductase from Escherichia coli
Biochemistry
26
4708-4716
1987
Escherichia coli
Reichard, P.; Ehrenberg, A.
Ribonucleotide reductase - a radical enzyme
Science
221
514-519
1983
Escherichia coli
Stubbe, J.; Ator, M.; Krenitsky, T.
Mechanism of ribonucleoside diphosphate reductase from Escherichia coli. Evidence for 3-C-H bond cleavage
J. Biol. Chem.
258
1625-1630
1983
Escherichia coli
Atkin, C.L.; Thelander, L.; Reichard, P.; Lang, G.
Iron and free radical in ribonucleotide reductase. Exchange of iron and Mossbauer spectroscopy of the protein B2 subunit of the Escherichia coli enzyme
J. Biol. Chem.
248
7464-7472
1973
Escherichia coli
Sjöberg, B.M.; Gräslund, A.; Loehr, J.S.; Loehr, T.M.
Ribonucleotide reductase: a structural study of the dimeric iron site
Biochem. Biophys. Res. Commun.
94
793-799
1980
Escherichia coli
Petersson, L.; Gräslund, A.; Ehrenberg, A.; Sjöberg, B.M.; Reichard, P.
The iron center in ribonucleotide reductase from Escherichia coli
J. Biol. Chem.
255
6706-6712
1980
Escherichia coli
Engström, Y.; Eriksson, S.; Thelander, L.; Akerman, M.
Ribonucleotide reductase from calf thymus. Purification and properties
Biochemistry
18
2941-2948
1979
Bos taurus, Escherichia coli
Jordan, A.; Pontis, E.; Atta, M.; Krook, M.; Gibert, I.; Barbe, J.; Reichard, P.
A second class I ribonucleotide reductase in Enterobacteriaceae: characterization of the Salmonella typhimurium enzyme
Proc. Natl. Acad. Sci. USA
91
12892-12896
1994
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
Tong, W.; Burdi, D.; Riggs-Gelasco, P.; Chen, S.; Edmondson, D.; Huynh, V.; Stubbe, J.; Han, S.; Arvai, A.; Tainer, J.
Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography
Biochemistry
37
5840-5848
1998
Escherichia coli (P69924)
Hamann, C.S.; Lentainge, S.; Li, L.S.; Salem, J.S.; Yang, F.D.; Cooperman, B.S.
Chimeric small subunit inhibitors of mammalian ribonucleotide reductase: a dual function for the R2 C-terminus?
Protein Eng.
11
219-224
1998
Escherichia coli, Mus musculus
Kolberg, M.; Logan, D.T.; Bleifuss, G.; Potsch, S.; Sjoberg, B.M.; Graslund, A.; Lubitz, W.; Lassmann, G.; Lendzian, F.
A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined X-ray diffraction and EPR/ENDOR studies
J. Biol. Chem.
280
11233-11246
2005
Escherichia coli (P69924), Escherichia coli
Birgander, P.L.; Bug, S.; Kasrayan, A.; Dahlroth, S.L.; Westman, M.; Gordon, E.; Sjoberg, B.M.
Nucleotide-dependent formation of catalytically competent dimers from engineered monomeric ribonucleotide reductase protein R1
J. Biol. Chem.
280
14997-15003
2005
Escherichia coli
Lang, P.; Gerez, C.; Tritsch, D.; Fontecave, M.; Biellmann, J.F.; Burger, A.
Synthesis of 8-vinyladenosine 5'-di- and 5'-triphosphate: evaluation of the diphosphate compound on ribonucleotide reductase
Tetrahedron
59
7315-7322
2003
Escherichia coli
-
Saleh, L.; Bollinger, J.M.
Cation mediation of radical transfer between Trp48 and Tyr356 during O2 activation by protein R2 of Escherichia coli ribonucleotide reductase: relevance to R1-R2 radical transfer in nucleotide reduction?
Biochemistry
45
8823-8830
2006
Escherichia coli
Cerqueira, N.M.; Fernandes, P.A.; Eriksson, L.A.; Ramos, M.J.
Dehydration of ribonucleotides catalyzed by ribonucleotide reductase: the role of the enzyme
Biophys. J.
90
2109-2119
2006
Escherichia coli
Pierce, B.S.; Hendrich, M.P.
Local and global effects of metal binding within the small subunit of ribonucleotide reductase
J. Am. Chem. Soc.
127
3613-3623
2005
Escherichia coli
Seyedsayamdost, M.R.; Stubbe, J.
Site-specific replacement of Y356 with 3,4-dihydroxyphenylalanine in the beta2 subunit of E. coli ribonucleotide reductase
J. Am. Chem. Soc.
128
2522-2523
2006
Escherichia coli
Nordlund, P.; Eklund, H.
Structure and function of the Escherichia coli ribonucleotide reductase protein R2
J. Mol. Biol.
232
123-164
1993
Escherichia coli
Zhang, Z.; Yang, K.; Chen, C.C.; Feser, J.; Huang, M.
Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1
Proc. Natl. Acad. Sci. USA
104
2217-2222
2007
Saccharomyces cerevisiae, Escherichia coli
Cerqueira, N.M.; Fernandes, P.A.; Ramos, M.J.
Ribonucleotide reductase: a critical enzyme for cancer chemotherapy and antiviral agents
Recent Pat. Anticancer Drug Discov.
2
11-29
2007
Escherichia coli
Reece, S.Y.; Seyedsayamdost, M.R.; Stubbe, J.; Nocera, D.G.
Photoactive peptides for light-initiated tyrosyl radical generation and transport into ribonucleotide reductase
J. Am. Chem. Soc.
129
8500-8509
2007
Escherichia coli
Jiang, W.; Yun, D.; Saleh, L.; Bollinger, J.M.; Krebs, C.
Formation and function of the manganese(IV)/iron(III) cofactor in Chlamydia trachomatis ribonucleotide reductase
Biochemistry
47
13736-13744
2008
Chlamydia trachomatis (O84835), Chlamydia trachomatis, Escherichia coli (P69924)
Jensen, K.P.; Bell, C.B.; Clay, M.D.; Solomon, E.I.
Peroxo-type intermediates in class I ribonucleotide reductase and related binuclear non-heme iron enzymes
J. Am. Chem. Soc.
131
12155-12171
2009
Escherichia coli (P69924)
Offenbacher, A.R.; Vassiliev, I.R.; Seyedsayamdost, M.R.; Stubbe, J.; Barry, B.A.
Redox-linked structural changes in ribonucleotide reductase
J. Am. Chem. Soc.
131
7496-7497
2009
Escherichia coli
Cotruvo, J.A.; Stubbe, J.
An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase
Biochemistry
49
1297-1309
2010
Escherichia coli
Seyedsayamdost, M.R.; Yee, C.S.; Stubbe, J.
Use of 2,3,5-F(3)Y-beta2 and 3-NH(2)Y-alpha2 to study proton-coupled electron transfer in Escherichia coli ribonucleotide reductase
Biochemistry
50
1403-1411
2011
Escherichia coli
Cotruvo, J.A.; Stubbe, J.
Escherichia coli class Ib ribonucleotide reductase contains a dimanganese(III)-tyrosyl radical cofactor in vivo
Biochemistry
50
1672-1681
2011
Escherichia coli, Escherichia coli GR536
Sanchez-Romero, M.A.; Molina, F.; Jimenez-Sanchez, A.
Correlation between ribonucleoside-diphosphate reductase and three replication proteins in Escherichia coli
BMC Mol. Biol.
11
11
2010
Escherichia coli
Holmgren, A.; Sengupta, R.
The use of thiols by ribonucleotide reductase
Free Radic. Biol. Med.
49
1617-1628
2010
Saccharomyces cerevisiae, Escherichia coli, Homo sapiens, Lactobacillus leichmannii, Mus musculus
Han, W.G.; Noodleman, L.
DFT calculations for intermediate and active states of the diiron center with a tryptophan or tyrosine radical in Escherichia coli ribonucleotide reductase
Inorg. Chem.
50
2302-2320
2011
Escherichia coli
Sanchez-Romero, M.A.; Molina, F.; Jimenez-Sanchez, A.
Organization of ribonucleoside-diphosphate reductase during multifork chromosome replication in Escherichia coli
Microbiology
157
2220-2225
2011
Escherichia coli, Escherichia coli K-12 CM735
Logan, D.
Closing the circle on ribonucleotide reductases
Nat. Struct. Mol. Biol.
18
251-253
2011
Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica subsp. enterica serovar Typhimurium
Boal, A.; Cotruvo Jr., J.; Stubbe, J.; Rosenzweig, A.
Structural basis for activation of class Ib ribonucleotide reductase
Science
329
1526-1530
2010
Escherichia coli (P37146)
Martin, J.E.; Imlay, J.A.
The alternative aerobic ribonucleotide reductase of Escherichia coli, NrdEF, is a manganese-dependent enzyme that enables cell replication during periods of iron starvation
Mol. Microbiol.
80
319-334
2011
Escherichia coli (P39452)
Ando, N.; Brignole, E.J.; Zimanyi, C.M.; Funk, M.A.; Yokoyama, K.; Asturias, F.J.; Stubbe, J.; Drennan, C.L.
Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase
Proc. Natl. Acad. Sci. USA
108
21046-21051
2011
Escherichia coli (P00452)
Zimanyi, C.M.; Chen, P.Y.; Kang, G.; Funk, M.A.; Drennan, C.L.
Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli
eLife
5
e07141
2016
Escherichia coli (P00452 and P69924), Escherichia coli
Olshansky, L.; Pizano, A.A.; Wei, Y.; Stubbe, J.; Nocera, D.G.
Kinetics of hydrogen atom abstraction from substrate by an active site thiyl radical in ribonucleotide reductase
J. Am. Chem. Soc.
136
16210-16216
2014
Escherichia coli
