Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.266: glucosyl-3-phosphoglycerate synthase

This is an abbreviated version!
For detailed information about glucosyl-3-phosphoglycerate synthase, go to the full flat file.

Word Map on EC 2.4.1.266

Reaction

NDP-glucose
+
3-phospho-D-glycerate
=
NDP
 +
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate

Synonyms

glucosyl-3-phosphoglycerate synthase, glucosyl-3-phosphoglycerate synthase/phosphatase, glucosylphosphoglycerate synthase, GpgS, GpgS protein, GpgS/P, More, MSMEG_5084, RB1005, Rv1208 protein

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.266 glucosyl-3-phosphoglycerate synthase

Natural Substrates Products

Natural Substrates Products on EC 2.4.1.266 - glucosyl-3-phosphoglycerate synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
GDP-glucose + 3-phospho-D-glycerate
GDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate
show the reaction diagram
synthesis of the solute glucosylglycerate proceeds via a two-step pathway involving glucosyl-3-phosphoglycerate synthase (GpgS) and glucosyl-3-phosphoglycerate phosphatase (GpgP). An mpgS gene coding for mannosyl-3-phosphoglycerate synthase (MpgS) is absent
-
-
?
UDP-glucose + 3-phospho-D-glycerate
UDP + 2-(O-alpha-D-glucopyranosyl)-3-phospho-D-glycerate
show the reaction diagram
the enzyme is involved in the phosphorylating pathway for synthesis of the solute mannosylglucosylglycerate. In Petrotoga mobilis two alternative pathways for the synthesis of mannosylglucosylglycerate are proposed. The first one is a a phosphorylating pathway (with a phosphorylated intermediate) from 3-phosphoglycerate and UDP-glucose to the final solute. The second nonphosphorylating pathway (no phosphorylated intermediates) could represent an alternative route for the synthesis of mannosylglucosylglycerate in Petrotoga mobilis that could lead to the direct conversion of glucosylglycerate and GDP-mannose to mannosylglucosylglycerate. Pathway multiplicity likely reflects a crucial role for mannosylglucosylglycerate in the physiology of Petrotoga mobilis mobilis during stress adaptation
-
-
?
UDP-glucose + 3-phospho-D-glycerate
UDP + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate
show the reaction diagram
UDP-glucose + 3-phospho-D-glycerate
UDP + 2-O-(alpha-D-glucosyl)-3-phospho-D-glycerate
show the reaction diagram
in Persephonella marina two pathways for synthesis of glucosylglycerate are present: 1. the single-step pathway in with glucosylglycerate synthase (Ggs) catalyzes the synthesis of 2-O-(alpha-D-glucosyl)-D-glycerate in one-step fop, ADP-glucose and D-glycerate, and 2. the two-step pathway in which glucosyl-3-phosphoglycerate synthase (GpgS) catalyzes the conversion of NDP-glucose and D-3-phosphoglycerate into glucosyl-3-phosphoglycerate, which is then converted to 2-O-(alpha-D-glucosyl)-D-glycerate by glucosyl-3-phosphoglycerate phosphatase (GpgP)
-
-
?
additional information
?
-