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1.20.4.2: methylarsonate reductase

This is an abbreviated version!
For detailed information about methylarsonate reductase, go to the full flat file.

Word Map on EC 1.20.4.2

Reaction

methylarsonate
+ 2 glutathione =
methylarsonite
+
glutathione disulfide
+
H2O

Synonyms

EC 1.97.1.7, GSTO1, GSTO2, MMA(V) reductase, monomethylarsonic acid (MMA V) reductase/hGSTO1, More, reductase, methylarsonate

ECTree

     1 Oxidoreductases
         1.20 Acting on phosphorus or arsenic in donors
             1.20.4 With disulfide as acceptor
                1.20.4.2 methylarsonate reductase

Substrates Products

Substrates Products on EC 1.20.4.2 - methylarsonate reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
arsenate + glutathione
arsenite + reduced glutathione
show the reaction diagram
-
-
-
-
?
dimethylarsonate + glutathione
dimethylarsonous acid
show the reaction diagram
-
-
-
-
?
methylarsonate + glutathione
methylarsonite + glutathione disulfide
show the reaction diagram
methylarsonate + glutathione
methylarsonite + oxidized glutathione
show the reaction diagram
-
rate-limiting enzyme in biotransformation of inorganic arsenite in rabbit liver
-
-
?
monomethylarsonate + glutathione
monomethylarsonous acid + oxidized glutathione
show the reaction diagram