1.14.14.173: 2,4,6-trichlorophenol monooxygenase

This is an abbreviated version!
For detailed information about 2,4,6-trichlorophenol monooxygenase, go to the full flat file.

Reaction

Synonyms

2,4,6-TCP 4-monooxygenase, 2,4,6-TCP monooxygenase, 2,4,6-trichlorophenol 4-monooxygenase, 2,4,6-trichlorophenol-4-monooxygenase, TCP-4-monooxygenase, tcpA

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.173 2,4,6-trichlorophenol monooxygenase

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Results	in table
1	Activating Compound
1	AA Sequence
3	Cloned(Commentary)
9	Cofactor
1	Crystallization (Commentary)
3	General Information
1	General Stability
9	Inhibitors
5	Metals/Ions
1	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
17	Organism
3	Pathway
1	pH Optimum
4	Purification (Commentary)
2	Reaction
13	Reference
4	Specific Activity [micromol/min/mg]
3	Storage Stability
70	Substrates and Products (Substrate)
10	Subunits
26	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]

Metals Ions

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Metals Ions on EC 1.14.14.173 - 2,4,6-trichlorophenol monooxygenase

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METALS and IONS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

Co2+

Cupriavidus sp. GP1

-

slight activation at 0.1 mM

757086

Fe2+

Cupriavidus sp. GP1

-

slight activation at 0.1 mM. The enzyme contains 0.2 mol of Fe per mol of the homotetrameric protein

757086

Fe3+

Cupriavidus sp. GP1

-

slight activation at 0.1 mM

757086

Ni2+

Cupriavidus sp. GP1

-

slight activation at 0.1 mM

757086

additional information

Cupriavidus sp. GP1

-

Fe2+ (0.2 mM) and Mg2+ (0.8 mM) do not enhance activity of the purified enzyme. No influence on enzyme activity is observed for 1 mM Mg2+, Ca2+, and Co2+

757086