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1.14.14.173: 2,4,6-trichlorophenol monooxygenase

This is an abbreviated version!
For detailed information about 2,4,6-trichlorophenol monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.173

Reaction

2,4,6-Trichlorophenol
+
FADH2
 +
O2
=
2,6-dichloro-1,4-benzoquinone
 +
Cl-
 +
FAD
 +
H2O

Synonyms

2,4,6-TCP 4-monooxygenase, 2,4,6-TCP monooxygenase, 2,4,6-trichlorophenol 4-monooxygenase, 2,4,6-trichlorophenol-4-monooxygenase, TCP-4-monooxygenase, tcpA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.173 2,4,6-trichlorophenol monooxygenase

Inhibitors

Inhibitors on EC 1.14.14.173 - 2,4,6-trichlorophenol monooxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4,6-Trichlorophenol
-
at 2,4,6-trichlorophenol concentrations higher than 0.1 mM, substrate inhibition which amounts to 43% at 0.2 mM 2,4,6-trichlorophenol and to 72% at 0.33 mM 2,4,6-trichlorophenol is observed
4-hydroxymercuribenzoate
-
62% inhibition at 0.1 mM
Acriflavine
-
complete inhibition at 0.1 mM
Cu2+
-
complete inhibition at 0.1 mM
Hg2+
-
87% inhibition at 0.1 mM
N-ethylmaleimide
-
42% inhibition at 0.1 mM
Quinacrine
-
complete inhibition at 0.1 mM
Zn2+
-
31% inhibition at 0.1 mM
additional information
-
not inhibited by menadione, metapyrone, EDTA, Tiron, 1,10-phenanthroline, KCN and sodium azide (1 mM each)
-