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EC Number	pH Optimum Minimum	pH Optimum Maximum	Commentary	Reference
3.2.2.22	-999	-	pH-dependency with stem-loop and unstructured DNA substrates, overview	664103
3.2.2.22	4	-	-	695562
3.2.2.22	4	-	assay at	664034
3.2.2.22	4	-	polynucleotide-adenosine glycosylase activity assay at	664818
3.2.2.22	4	-	polynucleotide:adenosine glycosidase	664180
3.2.2.22	4	-	polynucleotide:adenosine glycosidase activity	664180
3.2.2.22	4	-	reaction rate with MS 2 RNA and hdpDNA decreases progressively at values above	646903
3.2.2.22	4	-	the pH 4.0 catalytic optimum of RTA on 6mer to 18mer stem-loop DNA and RNA 28S SRL mimic oligonucleotides is known to result from the protonation of two ionizable residues on substrate and/or RTA	707125
3.2.2.22	5	-	-	709192
3.2.2.22	5	-	assay at	707114

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Release 2023.1 (January 2023)