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Reference on EC 5.4.99.1 - methylaspartate mutase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bothe, H.; Darley, D.J.; Albracht, S.P.; Gerfen, G.J.; Golding, B.T.; Buckel, W.
Identification of the 4-glutamyl radical as an intermediate in the carbon skeleton rearrangement catalyzed by coenzyme B12-dependent glutamate mutase from Clostridium cochlearium
Biochemistry
37
4105-4113
1998
Clostridium cochlearium
Manually annotated by BRENDA team
Ohmori, H.; Ishitani, H.; Sato, K.; Shimizu, S.; Fukui, S.
Vitamin B12 dependent glutamate mutase activity in photosynthetic bacteria
Biochem. Biophys. Res. Commun.
43
156-162
1971
Cereibacter sphaeroides, Rhodospirillum rubrum
Manually annotated by BRENDA team
Eagar, R.G.; Baltimore, B.G.; Herbst, M.M.; Barker, H.A.; Richards, J.H.
Mechanism of action of coenzyme B12. Hydrogen transfer in the isomerization of beta-methylaspartate to glutamate
Biochemistry
11
253-264
1972
Clostridium tetanomorphum
Manually annotated by BRENDA team
Ohmori, H.; Ishitani, H.; Sato, K.; Shimizu, S.; Fukui, S.
Metabolism of glutamate in purple nonsulfur bacteria. Participation of vitamin B12
Agric. Biol. Chem.
38
359-365
1974
Cereibacter sphaeroides, Rhodospirillum rubrum
-
Manually annotated by BRENDA team
Barker, H.A.
Glutamate mutase
Methods Enzymol.
13
319-330
1969
Clostridium tetanomorphum
-
Manually annotated by BRENDA team
Switzer, R.L.
Glutamate mutase
B12 (Dolphin, D. ed. ) Wiley, New York
2
289-305
1982
Acetoanaerobium sticklandii, Cereibacter sphaeroides, Clostridium cochlearium, Clostridium saccharobutyricum, Clostridium sp., Clostridium sp. SB4, Clostridium tetani, Clostridium tetanomorphum, no activity in Acidaminococcus fermentans, no activity in Clostridium microsporum, no activity in Fusobacterium fusiforme, no activity in Fusobacterium nucleatum, no activity in Micrococcus aerogenes, Rhodospirillum rubrum
-
Manually annotated by BRENDA team
Barker, H.A.
beta-Methylaspartate-glutamate mutase from Clostridium tetanomorphum
Methods Enzymol.
113
121-133
1985
Clostridium tetanomorphum
Manually annotated by BRENDA team
Barker, H.A.
Coenzyme B12-dependent mutases causing carbon chain rearrangements
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
6
509-537
1972
Clostridium cochlearium, Clostridium tetanomorphum, Cereibacter sphaeroides, Rhodospirillum rubrum
-
Manually annotated by BRENDA team
Marsh, E.N.G.
Tritium isotope effects in adenosylcobalamin-dependent glutamate mutase: implications for the mechanism
Biochemistry
34
7542-7547
1995
Clostridium tetanomorphum
Manually annotated by BRENDA team
Chen, H.P.; Marsh, E.N.G.
Adenosylcobalamin-dependent glutamate mutase: examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties
Biochemistry
36
14939-14945
1997
Clostridium cochlearium
Manually annotated by BRENDA team
Hartzoulakis, B.; Gani, D.
The mechanism of glutamate mutase: an unusually substrate-specific enzyme
Proc. Indian Acad. Sci. Chem. Sci.
106
1165-1176
1994
Clostridium tetanomorphum
-
Manually annotated by BRENDA team
Buckel, W.; Golding, B.T.
Glutamate and 2-methyleneglutarate mutase: from microbial curiosities to paradigms for coenzyme B12-dependent enzymes
Chem. Soc. Rev.
25
329-337
1996
Clostridium cochlearium, Clostridium tetanomorphum
-
Manually annotated by BRENDA team
Holloway, D.E.; Harding, S.E.; Marsh, E.N.G.
Adenosylcobalamin-dependent glutamate mutase: properties of a fusion protein in which the cobalamin-binding subunit is linked to the catalytic subunit
Biochem. J.
320
825-830
1996
Clostridium tetanomorphum
Manually annotated by BRENDA team
Holloway, D.E.; Chen, H.P.; Marsh, E.N.G.
Carboxymethylation of MutS-cysteine-15 specifically inactivates adenosylcobalamin-dependent glutamate mutase
J. Biol. Chem.
271
29121-29125
1996
Clostridium tetanomorphum
Manually annotated by BRENDA team
Holloway, D.E.; Marsh, E.N.G.
Adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum. Overexpression in Escherichia coli, purification, and characterization of the recombinant enzyme
J. Biol. Chem.
269
20425-20430
1994
Clostridium tetanomorphum
Manually annotated by BRENDA team
Leutbecher, U.; Bcher, R.; Linder, D.; Buckel, W.
Glutamate mutase from Clostridium cochlearium
Eur. J. Biochem.
205
759-765
1992
Clostridium cochlearium
Manually annotated by BRENDA team
Reitzer, R.; Krasser, M.; Jogl, G.; Buckel, W.; Bothe, H.; Kratky, C.
Crystallization and preliminary X-ray analysis of recombinant glutamate mutase and of the isolated component S from Clostridium cochlearium
Acta Crystallogr. Sect. D
54
1039-1042
1998
Clostridium cochlearium
Manually annotated by BRENDA team
Zelder, O.; Beatrix, B.; Leutbecher, U.; Buckel, W.
Characterization of the coenzyme-B12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli
Eur. J. Biochem.
226
577-585
1994
Clostridium cochlearium
Manually annotated by BRENDA team
Tollinger, M.; Konrat, R.; Hilbert, B.H.; Marsh, E.N.; Krautler, B.
How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum
Structure
15
1021-1033
1998
Clostridium tetanomorphum
Manually annotated by BRENDA team
Roymoulik, I.; Moon, N.; Dunham, W.R.; Ballou, D.P.; Marsh, E.N.
Rearrangement of L-2-hydroxyglutarate to L-threo-3-methylmalate catalyzed by adenosylcobalamin-dependent glutamate mutase
Biochemistry
39
10340-10346
2000
Clostridium cochlearium
Manually annotated by BRENDA team
Huhta, M.S.; Ciceri, D.; Golding, B.T.; Marsh, E.N.
A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase
Biochemistry
41
3200-3206
2002
Clostridium cochlearium
Manually annotated by BRENDA team
Xia, L.; Ballou, D.P.; Marsh, E.N.
Role of arg100 in the active site of adenosylcobalamin-dependent glutamate mutase
Biochemistry
43
3238-3245
2004
Clostridium cochlearium
Manually annotated by BRENDA team
Madhavapeddi, P.; Marsh, E.N.
The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase
Chem. Biol.
8
1143-1149
2001
Clostridium cochlearium
Manually annotated by BRENDA team
Hoffmann, B.; Tollinger, M.; Konrat, R.; Huhta, M.; Marsh, E.N.G.; Krautler, B.
A protein pre-organized to trap the nucleotide moiety of coenzyme B12: refined solution structure of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum
ChemBioChem
2
643-655
2001
Clostridium tetanomorphum
Manually annotated by BRENDA team
Gruber, K.; Kratky, C.
Coenzyme B(12) dependent glutamate mutase
Curr. Opin. Chem. Biol.
6
598-603
2002
Clostridium cochlearium
Manually annotated by BRENDA team
Hoffmann, B.; Konrat, R.; Bothe, H.; Buckel, W.; Krautler, B.
Structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium cochlearium
Eur. J. Biochem.
263
178-188
1999
Clostridium cochlearium
Manually annotated by BRENDA team
Chih, H.W.; Marsh, E.N.G.
Mechanism of glutamate mutase: identification and kinetic competence of acrylate and glycyl radical as intermediates in the rearrangement of glutamate to methylaspartate
J. Am. Chem. Soc.
122
10732-10733
2000
Clostridium cochlearium
-
Manually annotated by BRENDA team
Roymoulik, I.; Chen, H.P.; Marsh, E.N.
The reaction of the substrate analog 2-ketoglutarate with adenosylcobalamin-dependent glutamate mutase
J. Biol. Chem.
274
11619-11622
1999
Clostridium cochlearium
Manually annotated by BRENDA team
Tollinger, M.; Eichmuller, C.; Konrat, R.; Huhta, M.S.; Marsh, E.N.; Krautler, B.
The B(12)-binding subunit of glutamate mutase from Clostridium tetanomorphum traps the nucleotide moiety of coenzyme B(12)
J. Mol. Biol.
309
777-791
2001
Clostridium tetanomorphum
Manually annotated by BRENDA team
Reitzer, R.; Gruber, K.; Jogl, G.; Wagner, U.G.; Bothe, H.; Buckel, W.; Kratky, C.
Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights
Structure
7
891-902
1999
Clostridium cochlearium
Manually annotated by BRENDA team
Cheng, M.C.; Marsh, E.N.
Pre-steady-state measurement of intrinsic secondary tritium isotope effects associated with the homolysis of adenosylcobalamin and the formation of 5'-deoxyadensosine in glutamate mutase
Biochemistry
43
2155-2158
2004
Clostridium cochlearium
Manually annotated by BRENDA team
Brooks, A.J.; Fox, C.C.; Marsh, E.N.; Vlasie, M.; Banerjee, R.; Brunold, T.C.
Electronic structure studies of the adenosylcobalamin cofactor in glutamate mutase
Biochemistry
44
15167-15181
2005
Clostridium cochlearium
Manually annotated by BRENDA team
Cheng, M.C.; Marsh, E.N.
Isotope effects for deuterium transfer between substrate and coenzyme in adenosylcobalamin-dependent glutamate mutase
Biochemistry
44
2686-2691
2005
Clostridium cochlearium
Manually annotated by BRENDA team
Sension, R.J.; Cole, A.G.; Harris, A.D.; Fox, C.C.; Woodbury, N.W.; Lin, S.; Marsh, E.N.G.
Photolysis and recombination of adenosylcobalamin bound to glutamate mutase
J. Am. Chem. Soc.
126
1598-1599
2004
Clostridium cochlearium
Manually annotated by BRENDA team
Sension, R.J.; Harris, D.A.; Stickrath, A.; Cole, A.G.; Fox, C.C.; Marsh, E.N.G.
Time-resolved measurements of the photolysis and recombination of adenosylcobalamin bound to glutamate mutase
J. Phys. Chem. B
109
18146-18152
2005
Clostridium cochlearium
Manually annotated by BRENDA team
Li, Y.; Ling, H.; Li, W.; Tan, H.
Improvement of nikkomycin production by enhanced copy of sanU and sanV in Streptomyces ansochromogenes and characterization of a novel glutamate mutase encoded by sanU and sanV
Metab. Eng.
7
165-173
2005
Streptomyces ansochromogenes
Manually annotated by BRENDA team
Patwardhan, A.; Marsh, E.N.
Changes in the free energy profile of glutamate mutase imparted by the mutation of an active site arginine residue to lysine
Arch. Biochem. Biophys.
461
194-199
2007
Clostridium cochlearium
Manually annotated by BRENDA team
Yoon, M.; Patwardhan, A.; Qiao, C.; Mansoorabadi, S.O.; Menefee, A.L.; Reed, G.H.; Marsh, E.N.
Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate
Biochemistry
45
11650-11657
2006
Clostridium cochlearium
Manually annotated by BRENDA team
Cheng, M.C.; Marsh, E.N.
Evidence for coupled motion and hydrogen tunneling of the reaction catalyzed by glutamate mutase
Biochemistry
46
883-889
2007
Clostridium cochlearium
Manually annotated by BRENDA team
Weng, Y.; Hsu, F.; Yang, W.; Chen, H.
Optimization of the overexpression of glutamate mutase S component under the control of T7 system by using lactose and IPTG as the inducers
Enzyme Microb. Technol.
38
465-469
2006
Clostridium tetanomorphum
-
Manually annotated by BRENDA team
Sandala, G.M.; Smith, D.M.; Marsh, E.N.; Radom, L.
Toward an improved understanding of the glutamate mutase system
J. Am. Chem. Soc.
129
1623-1633
2007
Clostridium cochlearium
Manually annotated by BRENDA team
Chen, H.P.; Hsu, H.J.; Hsu, F.C.; Lai, C.C.; Hsu, C.H.
Interactions between coenzyme B analogs and adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum
FEBS J.
275
5960-5968
2008
Clostridium tetanomorphum
Manually annotated by BRENDA team
Yoon, M.; Song, H.; Hakansson, K.; Marsh, E.N.
Hydrogen tunneling in adenosylcobalamin-dependent glutamate mutase: evidence from intrinsic kinetic isotope effects measured by intramolecular competition
Biochemistry
49
3168-3173
2010
Homo sapiens
Manually annotated by BRENDA team
Ramezani, M.; Resmer, K.L.; White, R.L.
Glutamate racemization and catabolism in Fusobacterium varium
FEBS J.
278
2540-2551
2011
Fusobacterium varium
Manually annotated by BRENDA team
Kozlowski, P.M.; Kamachi, T.; Kumar, M.; Nakayama, T.; Yoshizawa, K.
Theoretical analysis of the diradical nature of adenosylcobalamin cofactor-tyrosine complex in B12-dependent mutases: inspiring PCET-driven enzymatic catalysis
J. Phys. Chem. B
114
5928-5939
2010
Clostridium cochlearium (P80077), Clostridium cochlearium (P80078)
Manually annotated by BRENDA team
Biedendieck, R.; Malten, M.; Barg, H.; Bunk, B.; Martens, J.H.; Deery, E.; Leech, H.; Warren, M.J.; Jahn, D.
Metabolic engineering of cobalamin (vitamin B12) production in Bacillus megaterium
Microb. Biotechnol.
3
24-37
2010
Priestia megaterium
Manually annotated by BRENDA team
Rommel, J.B.; Kaestner, J.
The fragmentation-recombination mechanism of the enzyme glutamate mutase studied by QM/MM simulations
J. Am. Chem. Soc.
133
10195-10203
2011
Clostridium cochlearium
Manually annotated by BRENDA team
Rommel, J.B.; Liu, Y.; Werner, H.J.; Kaestner, J.
Role of tunneling in the enzyme glutamate mutase
J. Phys. Chem. B
116
13682-13689
2012
Clostridium cochlearium
Manually annotated by BRENDA team
Wang, J.; Zhang, K.
Production of mesaconate in Escherichia coli by engineered glutamate mutase pathway
Metab. Eng.
30
190-196
2015
no activity in Escherichia coli, Clostridium tetanomorphum (Q05488 AND Q05509), Clostridium tetanomorphum, Clostridium tetanomorphum ATCC 15920 (Q05488 AND Q05509)
Manually annotated by BRENDA team