Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 3.4.24.11 - neprilysin and Organism(s) Rattus norvegicus and UniProt Accession P07861

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stephenson, S.L.; Kenny, A.J.
The metabolism of neuropeptides. Hydrolysis of peptides by the phosphoramidon-insensitive rat kidney enzyme endopeptidase-2 and by rat microvillar membranes
Biochem. J.
255
45-51
1988
Rattus norvegicus
Manually annotated by BRENDA team
Danilewicz, J.C.; Barclay, P.L.; Barnish, I.T.; Brown, D.; Campbell, S.F.; James, K.; Samuels, G.M.R.; Terrett, N.K.; Wythes, M.J.
UK-69,578, a novel inhibitor of EC 3.4.24.11 which increases endogenous ANF levels and is natriuretic and diuretic
Biochem. Biophys. Res. Commun.
164
58-65
1989
Rattus norvegicus
Manually annotated by BRENDA team
Erds, E.G.; Skidgel, R.A.
Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones
FASEB J.
3
145-151
1989
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Kanazawa, M.; Casley, D.J.; Sybertz, E.J.; Haslanger, M.F.; Johnston, C.I.
Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor
J. Pharmacol. Exp. Ther.
261
1231-1237
1992
Rattus norvegicus
Manually annotated by BRENDA team
Zajac, J.M.; Charnay, Y.; Soleilhac, J.M.; Sales, N.; Roques, B.P.
Enkephalin-degrading enzymes and angiotensin-converting enzyme in human and rat meninges
FEBS Lett.
216
118-122
1987
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Malfroy, B.; Burnier, J.
New substrates for enkephalinase (neutral endopeptidase) based on fluorescence energy transfer
Biochem. Biophys. Res. Commun.
143
58-66
1987
Rattus norvegicus
Manually annotated by BRENDA team
Malfroy, B.; Schofield, P.R.; Kuang, W.J.; Seeburg, P.H.; Mason, A.J.; Henzel, W.J.
Molecular cloning and amino acid sequence of rat enkephalinase
Biochem. Biophys. Res. Commun.
144
59-66
1987
Rattus norvegicus
Manually annotated by BRENDA team
Waksman, G.; Hamel, E.; Delay-Goyet, P.; Roques, B.P.
Neuronal localization of the neutral endopeptidase enkephalinase in rat brain revealed by lesions and autoradiography
EMBO J.
5
3163-3166
1986
Rattus norvegicus
Manually annotated by BRENDA team
Jackson, D.G.; Hersh, L.B.
Reaction of neutral endopeptidase 24.11 (enkephalinase) with arginine reagents
J. Biol. Chem.
261
8649-8654
1986
Rattus norvegicus
Manually annotated by BRENDA team
Malfroy, B.; Schwartz, J.C.
Properties of enkephalinase from rat kidney: comparison of dipeptidyl-carboxypeptidase and endopeptidase activities
Biochem. Biophys. Res. Commun.
106
276-285
1982
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Roques, B.P.; Noble, F.; Dauge, V.; Fournie-Zaluski, M.C.; Beaumont, A.
Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology
Pharmacol. Rev.
45
87-146
1993
Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Welches, W.R.; Broshihan, K.B.; Ferrario, C.M.
A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11
Life Sci.
52
1461-1480
1993
Bos taurus, Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Schulz, R.; Sakane, Y.; Berry, C.; Ghai, R.
Characterisation of neutral endopeptidase 3.4.24.11 (NEP) in the kidney: comparison between normotensive, genetically hypertensive and experimentally hypertensive rats
J. Enzyme Inhib.
4
347-358
1991
Rattus norvegicus
Manually annotated by BRENDA team
Spillantini, M.G.; Sicuteri, F.; Salmon, S.; Malfroy, B.
Characterization of endopeptidase 3.4.24.11 ( enkephalinase ) activity in human plasma and cerebrospinal fluid
Biochem. Pharmacol.
39
1353-1356
1990
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Li, C.; Hersh, L.B.
Neprilysin: assay methods, purification, and characterization
Methods Enzymol.
248
253-263
1995
Rattus norvegicus
Manually annotated by BRENDA team
Sansoe, G.; Aragno, M.; Mastrocola, R.; Cutrin, J.C.; Silvano, S.; Mengozzi, G.; Smedile, A.; Rosina, F.; Danni, O.; Rizzetto, M.
Overexpression of kidney neutral endopeptidase (EC 3.4.24.11) and renal function in experimental cirrhosis
Am. J. Physiol. Renal Physiol.
290
F1337-F1343
2006
Rattus norvegicus
Manually annotated by BRENDA team
Huang, J.; Guan, H.; Booze, R.M.; Eckman, C.B.; Hersh, L.B.
Estrogen regulates neprilysin activity in rat brain
Neurosci. Lett.
367
85-87
2004
Rattus norvegicus
Manually annotated by BRENDA team
Jiang, W.; Jiang, H.F.; Cai, D.Y.; Pan, C.S.; Qi, Y.F.; Pang, Y.Z.; Tang, C.S.
Relationship between contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of rats in septic shock
Regul. Pept.
118
199-208
2004
Rattus norvegicus
Manually annotated by BRENDA team
Schmid, C.; Ghirlanda-Keller, C.; Gosteli-Peter, M.
Ascorbic acid decreases neutral endopeptidase activity in cultured osteoblastic cells
Regul. Pept.
130
57-66
2005
Rattus norvegicus (P07861)
Manually annotated by BRENDA team
de Gortari, P.; Vargas, M.A.; Martinez, A.; Garcia-Vazquez, A.I.; Uribe, R.M.; Chavez-Gutierrez, L.; Magdaleno, V.; Boileau, G.; Charli, J.L.; Joseph-Bravo, P.
Stage-specific modulation of neprilysin and aminopeptidase N in the limbic system during kindling progression
J. Mol. Neurosci.
33
252-261
2007
Rattus norvegicus
Manually annotated by BRENDA team
Thomas, C.J.; McAllen, R.M.; Salo, L.M.; Woods, R.L.
Restorative effect of atrial natriuretic peptide or chronic neutral endopeptidase inhibition on blunted cardiopulmonary vagal reflexes in aged rats
Hypertension
52
696-701
2008
Rattus norvegicus
Manually annotated by BRENDA team
Mak, I.T.; Kramer, J.H.; Chmielinska, J.J.; Khalid, M.H.; Landgraf, K.M.; Weglicki, W.B.
Inhibition of neutral endopeptidase potentiates neutrophil activation during Mg-deficiency in the rat
Inflamm. Res.
57
300-305
2008
Rattus norvegicus
Manually annotated by BRENDA team
Yao, M.; Nguyen, T.V.; Rosario, E.R.; Ramsden, M.; Pike, C.J.
Androgens regulate neprilysin expression: role in reducing beta-amyloid levels
J. Neurochem.
105
2477-2488
2008
Rattus norvegicus
Manually annotated by BRENDA team
Burgos-Ramos, E.; Puebla-Jimenez, L.; Arilla-Ferreiro, E.
Minocycline prevents Abeta(25-35)-induced reduction of somatostatin and neprilysin content in rat temporal cortex
Life Sci.
84
205-210
2009
Rattus norvegicus
Manually annotated by BRENDA team
Maeshiro, K.; Takamori, S.; Mifune, H.; Matsuo, T.; Kimura, N.Y.; Honda, J.; Shirouzu, K.
Changes in A-type natriuretic peptide and its receptors induced by a neutral endopeptidase inhibitor in a rat model of sepsis
Surg. Today
38
130-134
2008
Rattus norvegicus
Manually annotated by BRENDA team
Belyaev, N.; Nalivaeva, N.; Makova, N.; Turner, A.
Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: Implications for Alzheimer disease
EMBO Rep.
10
94-100
2009
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Davies, K.P.
The role of opiorphins (endogenous neutral endopeptidase inhibitors) in urogenital smooth muscle biology
J. Sex Med.
6 Suppl 3
286-291
2009
Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Gu, J.; Noe, A.; Chandra, P.; Al-Fayoumi, S.; Ligueros-Saylan, M.; Sarangapani, R.; Maahs, S.; Ksander, G.; Rigel, D.F.; Jeng, A.Y.; Lin, T.H.; Zheng, W.; Dole, W.P.
Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi)
J. Clin. Pharmacol.
50
401-414
2010
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Morales-Mulia, M.; de Gortari, P.; Amaya, M.I.; Mendez, M.
Activity and expression of enkephalinase and aminopeptidase N in regions of the mesocorticolimbic system are selectively modified by acute ethanol administration
J. Mol. Neurosci.
46
58-67
2012
Rattus norvegicus
Manually annotated by BRENDA team
Marr, R.A.; Hafez, D.M.
Amyloid-beta and Alzheimers disease: the role of neprilysin-2 in amyloid-beta clearance
Front. Aging Neurosci.
6
187
2014
Rattus norvegicus, Homo sapiens (P08473), Mus musculus (Q61391)
Manually annotated by BRENDA team
Morisaki, N.; Ohuchi, A.; Moriwaki, S.
The role of neprilysin in regulating the hair cycle
PLoS ONE
8
e55947
2013
Rattus norvegicus (P07861), Homo sapiens (P08473), Mus musculus (Q61391)
Manually annotated by BRENDA team
de Oliveira, R.W.; Julian, G.S.; Perry, J.C.; Tufik, S.; Chagas, J.R.
Chronic intermittent hypoxia induces changes on the expression and activity of neprilysin (EC 3.4.24.11) in the brain of rats
Neurosci. Lett.
678
43-47
2018
Rattus norvegicus (P07861), Rattus norvegicus Wistar-Hannover (P07861)
Manually annotated by BRENDA team