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ATP + Gcn4 protein
ADP + phosphorylated Gcn4 protein
-
-
-
?
ATP + Glc8 protein
ADP + phosphorylated Glc8 protein
-
-
-
?
ATP + Gsy2 protein
ADP + phosphorylated Gsy2 protein
-
-
-
?
ATP + Pho4 protein
ADP + phosphorylated Pho4 protein
-
-
-
?
ATP + Rga2 protein
ADP + phosphorylated Rga2 protein
-
-
-
?
ATP + Rim 15 protein
ADP + phosphorylated Rim15 protein
-
-
-
?
ATP + Rvs167 protein
ADP + phosphorylated Rvs167 protein
-
-
-
?
ATP + Sic1 protein
ADP + phosphorylated Sic1 protein
-
-
-
?
ATP + Whi5 G1 protein
ADP + phosphorylated Whi5 G1 protein
-
-
-
?
ATP + a protein
ADP + a phosphoprotein
-
-
-
-
?
ATP + ADAQHATPPKKKRKVEDPKDF
ADP + ADAQHAT(P)PPKKKRKVEDPKDF
-
a histone peptide substrate
-
-
?
ATP + Bni4
ADP + phosphorylated Bni4
-
-
-
-
?
ATP + Boi1
ADP + phosphorylated Boi1
-
-
-
-
?
ATP + Boi2
ADP + phosphorylated Boi2
-
-
-
-
?
ATP + Cdc6
ADP + phosphorylated Cdc6
-
-
-
-
?
ATP + Clb6
ADP + phosphorylated Clb6
-
-
-
-
?
ATP + Cln3 protein
ADP + Cln3 phosphoprotein
-
recombinant His-tagged Cln3 protein is phosphorylated by Pho85/Pho80 complexes at S449 and T520. Cdc28 phosphorylates Cln3 to a greater extent than Pho85, probably because it phosphorylates Cln3 at more sites in the PEST region than Pho85
-
-
?
ATP + cyclin-dependent kinase
ADP + phosphorylated cyclin-dependent kinase
-
-
-
?
ATP + Fin1
ADP + phosphorylated Fin1
-
-
-
-
?
ATP + Fkh2p
ADP + phosphorylated Fkh2p
ATP + histone H1
ADP + phosphorylated histone H1
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 2
ADP + phosphorylated mini-chromosomemaintenance protein 2
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 3
ADP + phosphorylated mini-chromosomemaintenance protein 3
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 4
ADP + phosphorylated mini-chromosomemaintenance protein 4
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 5
ADP + phosphorylated mini-chromosomemaintenance protein 5
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 6
ADP + phosphorylated mini-chromosomemaintenance protein 6
-
-
-
-
?
ATP + mini-chromosomemaintenance protein 7
ADP + phosphorylated mini-chromosomemaintenance protein 7
-
-
-
-
?
ATP + origin recognition complex 1
ADP + phosphorylated origin recognition complex 1
-
-
-
-
?
ATP + origin recognition complex 2
ADP + phosphorylated origin recognition complex 2
-
-
-
-
?
ATP + origin recognition complex 3
ADP + phosphorylated origin recognition complex 3
-
-
-
-
?
ATP + origin recognition complex 4
ADP + phosphorylated origin recognition complex 4
-
-
-
-
?
ATP + origin recognition complex 5
ADP + phosphorylated origin recognition complex 5
-
-
-
-
?
ATP + origin recognition complex 6
ADP + phosphorylated origin recognition complex 6
-
-
-
-
?
ATP + Pho81
ADP + phosphorylated Pho81
-
-
phosphorylated Pho81 is an inhibitor for Pho85
-
?
ATP + Rad9 protein
ADP + Rad9 phosphoprotein
ATP + Rga2
ADP + phosphorylated Rga2
-
-
-
-
?
ATP + RhoGEF Tus1p
ADP + phosphorylated RhoGEF Tus1p
-
-
-
-
?
ATP + RNA polymerase II largest subunit
ADP + phosphorylated RNA polymerase II largest subunit
specifically hyperphosphorylates the carboxyl-terminal
-
-
?
ATP + Sic1
ADP + phosphorylated Sic1
ATP + Swi5
ADP + phosphorylated Swi5
-
-
-
-
?
ATP + Swi6
ADP + phosphorylated Swi6
-
substrate of cdc28p
-
-
?
ATP + Vac17
ADP + phosphorylated Vac17
-
-
-
-
?
additional information
?
-
ATP + Fkh2p
ADP + phosphorylated Fkh2p
-
phosphorylation of forkhead transcription factor Fkh2p is part of regulation of cell cycle-specific gene expression, e.g. of the CLB2 cluster, Fkh2p phosphorylation by Cdc28p is regulated by complex formation with Mcm1p and Ndd1p, and phosphorylation, overview
-
-
?
ATP + Fkh2p
ADP + phosphorylated Fkh2p
-
forkhead transcription factor Fkh2p, C-terminally phosphorylation of Fkh2p promotes interaction with the activator Ndd1p, which becomes also phosphorylated, activity with Fkh2p mutants, overview
-
-
?
ATP + Rad9 protein
ADP + Rad9 phosphoprotein
-
a DNA damage response mediator
-
-
?
ATP + Rad9 protein
ADP + Rad9 phosphoprotein
-
a DNA damage response mediator, phosphorylaation at Thr125 and Thr143
-
-
?
ATP + Sic1
ADP + phosphorylated Sic1
-
-
-
-
?
ATP + Sic1
ADP + phosphorylated Sic1
-
Glc8 function is dependent on phosphorylation at Thr-118, which is phosphorylated by Pho85 in conjunction with cyclins Pcl6 and Pcl7, and possibly Pcl8 and Pcl10
-
-
?
additional information
?
-
negative regulatory factors of the PHO system
-
-
?
additional information
?
-
-
negative regulatory factors of the PHO system
-
-
?
additional information
?
-
the enzyme requires no phosphorylation for kinase activity
-
-
?
additional information
?
-
-
the enzyme requires no phosphorylation for kinase activity
-
-
?
additional information
?
-
enzyme is required for initiation of meiosis and sporulation
-
-
?
additional information
?
-
Kin28 may be a cyclin dependent kinase which is required for cell proliferation
-
-
?
additional information
?
-
enzyme is required for induction of meiosis
-
-
?
additional information
?
-
-
determination of cyclin specificity of Cdk1 during cell cycle using mutant Cdk1-as1 with an enlarged ATP binding site, overview
-
-
?
additional information
?
-
-
determination of cyclin specificity of Cdk1 with different enzyme substrates using mutant Cdk1-as1 with an enlarged ATP binding site, overview
-
-
?
additional information
?
-
-
Cdk activity is required to fire origins of DNA replication and to prevent 'licensing' (establishing the competence) of additional origins after replication initiation
-
-
?
additional information
?
-
-
once-per-cell-cycle replication is enforced by cyclin-Cdk-dependent phosphorylation of the prereplicative complex components Mcm2-7, Cdc6, and Orc1-6
-
-
?
additional information
?
-
-
Cdk1 controls timing of vacuole movement and regulates vacuole inheritance
-
-
?
additional information
?
-
-
Pho85 is a proline-directed kinase that preferentially phosphorylates the consensus sequence S/T-P-X-I/L. Cln3 contains two of these sites (Ser449 and Thr520) located precisely at the ends of the PEST region. Cln3 is an in vitro substrate of Pho85, and both proteins interact in vivo, Cln3 is a molecular target of the Pho85 kinase
-
-
?
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10
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11
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brenda
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brenda
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11
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1
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The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI
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