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Literature summary for 2.7.11.22 extracted from
- Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast (2007), Mol. Microbiol., 66, 303-314.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Pho81 phosphoprotein | - |
Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + Bni4 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Bni4 | - |
? |  |
| ATP + Boi1 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Boi1 | - |
? | |
| ATP + Boi2 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Boi2 | - |
? | |
| ATP + Clb6 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Clb6 | - |
? | |
| ATP + Pho81 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Pho81 | phosphorylated Pho81 is an inhibitor for Pho85 | ? | |
| ATP + Rga2 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Rga2 | - |
? | |
| ATP + Sic1 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Sic1 | - |
? | |
| ATP + Sic1 | Glc8 function is dependent on phosphorylation at Thr-118, which is phosphorylated by Pho85 in conjunction with cyclins Pcl6 and Pcl7, and possibly Pcl8 and Pcl10 | Saccharomyces cerevisiae | ADP + phosphorylated Sic1 | - |
? | |
| ATP + Swi5 | - |
Saccharomyces cerevisiae | ADP + phosphorylated Swi5 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CDK | - |
Saccharomyces cerevisiae |
| PHO85 | multifunctional cyclin-dependent protein kinase | Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cyclin Pcl1 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl10 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl2 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl3 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl4 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl5 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl6 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl7 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl8 | - |
Saccharomyces cerevisiae | |
| cyclin Pcl9 | - |
Saccharomyces cerevisiae | |
| cyclin Pho80 | - |
Saccharomyces cerevisiae | |
| additional information | Pho85 associates with 10 Pho85 cyclins | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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