Reference on EC 2.7.11.13 - protein kinase C and Organism(s) Rattus norvegicus and UniProt Accession Q64617
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Nishizuka, Y.
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
Nature
334
661-665
1988
Bos taurus (P04409), Bos taurus (P05126), Rattus norvegicus (P05696), Oryctolagus cuniculus (P10102)
Ono, Y.; Fujii, T.; Igarashi, K.; Kikkawa, U.; Ogita, K.; Nishizuka, Y.
Nucleotide sequences of cDNAs for alpha and gamma subspecies of rat brain protein kinase C
Nucleic Acids Res.
16
5199-5200
1988
Rattus norvegicus (P05696), Mus musculus (P63318)
Kikkawa, U.; Ogita, K.; Ono, Y.; Asaoka, Y.; Shearman, M.S.; Fujii, T.; Ase, K.; Sekiguchi, K.; Igarashi, K.; Nishizuka, Y.
The common structure and activities of four subspecies of rat brain protein kinase C family
FEBS Lett.
223
212-216
1987
Rattus norvegicus (P05696)
Ueyama, T.; Ren, Y.; Ohmori, S.; Sakai, K.; Tamaki, N.; Saito, N.
cDNA cloning of an alternative splicing variant of protein kinase C delta (PKC deltaIII), a new truncated form of PKCdelta, in rats
Biochem. Biophys. Res. Commun.
269
557-563
2000
Rattus norvegicus (P09215)
Kurkinen, K.M.; Keinanen, R.A.; Karhu, R.; Koistinaho, J.
Genomic structure and chromosomal localization of the rat protein kinase Cdelta-gene
Gene
242
115-123
2000
Rattus norvegicus (P09215)
Pappa, H.; Murray-Rust, J.; Dekker, L.V.; Parker, P.J.; McDonald, N.Q.
Crystal structure of the C2 domain from protein kinase C-delta
Structure
6
885-894
1998
Rattus norvegicus (P09215)
Garcia-Paramio, P.; Cabrerizo, Y.; Bornancin, F.; Parker, P.J.
The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation
Biochem. J.
333
631-636
1998
Rattus norvegicus (P09215)
-
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
The structure, expression, and properties of additional members of the protein kinase C family
J. Biol. Chem.
263
6927-6932
1988
Rattus norvegicus (P09215), Rattus norvegicus (P09216), Rattus norvegicus (P09217)
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
Identification of three additional members of rat protein kinase C family: delta-, epsilon- and zeta-subspecies
FEBS Lett.
226
125-128
1987
Rattus norvegicus (P09215), Rattus norvegicus (P09216), Rattus norvegicus (P09217)
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y.
Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties
Proc. Natl. Acad. Sci. USA
86
3099-3103
1989
Rattus norvegicus (P09217)
Mukai, H.; Ono, Y.
A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C
Biochem. Biophys. Res. Commun.
199
897-904
1994
Homo sapiens (Q16512), Homo sapiens, Rattus norvegicus (Q63433)
Morrice, N.A.; Gabrielli, B.; Kemp, B.E.; Wettenhall, R.E.
A cardiolipin-activated protein kinase from rat liver structurally distinct from the protein kinases C
J. Biol. Chem.
269
20040-20046
1994
Rattus norvegicus (Q63433)
Dekker, L.V.; Parker, P.J.; McIntyre, P.
Biochemical properties of rat protein kinase C-eta expressed in COS cells
FEBS Lett.
312
195-199
1992
Rattus norvegicus (Q64617)
Choi, B.H.; Chae, H.D.; Park, T.J.; Oh, J.; Lim, J.; Kang, S.S.; Ha, H.; Kim, K.T.
Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase
J. Neurochem.
90
442-454
2004
Rattus norvegicus
Beltowski, J.; Marciniak, A.; Jamroz-Wisniewska, A.; Borkowska, E.; Wojcicka, G.
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C
Acta Biochim. Pol.
51
757-772
2004
Rattus norvegicus
Barman, S.A.; Zhu, S.; White, R.E.
Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle
Am. J. Physiol.
286
L149-155
2004
Rattus norvegicus
Duran, M.J.; Pierre, S.V.; Carr, D.L.; Pressley, T.A.
The isoform-specific region of the Na,K-ATPase catalytic subunit: role in enzyme kinetics and regulation by protein kinase C
Biochemistry
43
16174-16183
2004
Rattus norvegicus
Yang, J.H.; Derr-Yellin, E.C.; Kodavanti, P.R.
Alterations in brain protein kinase C isoforms following developmental exposure to a polychlorinated biphenyl mixture
Brain Res. Mol. Brain Res.
111
123-135
2003
Rattus norvegicus
Hung, A.C.; Chu, Y.J.; Lin, Y.H.; Weng, J.Y.; Chen, H.B.; Au, Y.C.; Sun, S.H.
Roles of protein kinase C in regulation of P2X7 receptor-mediated calcium signalling of cultured type-2 astrocyte cell line, RBA-2
Cell. Signal.
17
1384-1396
2005
Rattus norvegicus
Geeraert, V.; Dupont, J.L.; Grant, N.J.; Huvet, C.; Chasserot-Golaz, S.; Janoshazi, A.; Procksch, O.; de Barry, J.
F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cells
Exp. Cell Res.
289
222-236
2003
Rattus norvegicus
Helliwell, P.A.; Rumsby, M.G.; Kellett, G.L.
Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent pathways
J. Biol. Chem.
278
28644-28650
2003
Rattus norvegicus
Ananthanarayanan, B.; Stahelin, R.V.; Digman, M.A.; Cho, W.
Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains
J. Biol. Chem.
278
46886-46894
2003
Rattus norvegicus
Ranganathan, S.; Liu, C.X.; Migliorini, M.M.; Von Arnim, C.A.; Peltan, I.D.; Mikhailenko, I.; Hyman, B.T.; Strickland, D.K.
Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules
J. Biol. Chem.
279
40536-40544
2004
Homo sapiens, Rattus norvegicus
Johnson, L.A.; Guptaroy, B.; Lund, D.; Shamban, S.; Gnegy, M.E.
Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta
J. Biol. Chem.
280
10914-10919
2005
Rattus norvegicus
Tsuda, K.; Tsuda, S.; Nishio, I.
Role of protein kinase C in the regulation of acetylcholine release in the central nervous system of spontaneously hypertensive rats
J. Cardiovasc. Pharmacol.
41 Suppl 1
S57-60
2003
Rattus norvegicus
Gu, J.L.; Lu, W.; Xia, C.; Wu, X.; Liu, M.
Regulation of hematopoietic-specific G-protein Galpha15 and Galpha16 by protein kinase C
J. Cell. Biochem.
88
1101-1111
2003
Rattus norvegicus
Bayer, A.L.; Heidkamp, M.C.; Patel, N.; Porter, M.; Engman, S.; Samarel, A.M.
Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy
Mol. Cell. Biochem.
242
145-152
2003
Rattus norvegicus
Larsen, G.A.; Berg-Johnsen, J.; Moe, M.C.; Vinje, M.L.
Calcium-dependent protein kinase C activation in acutely isolated neurons during oxygen and glucose deprivation
Neurochem. Res.
29
1931-1937
2004
Rattus norvegicus
Mahmmoud, Y.A.
Modulation of protein kinase C by curcumin; inhibition and activation switched by calcium ions
Br. J. Pharmacol.
150
200-208
2007
Rattus norvegicus
Curia, G.; Aracri, P.; Colombo, E.; Scalmani, P.; Mantegazza, M.; Avanzini, G.; Franceschetti, S.
Phosphorylation of sodium channels mediated by protein kinase-C modulates inhibition by topiramate of tetrodotoxin-sensitive transient sodium current
Br. J. Pharmacol.
150
792-797
2007
Rattus norvegicus
Popp, R.L.; Velasquez, O.; Bland, J.; Hughes, P.
Characterization of protein kinase C isoforms in primary cultured cerebellar granule cells
Brain Res.
1083
70-84
2006
Rattus norvegicus
Beaudry, H.; Gendron, L.; Guimond, M.O.; Payet, M.D.; Gallo-Payet, N.
Involvement of protein kinase C alpha (PKC alpha) in the early action of angiotensin II type 2 (AT2) effects on neurite outgrowth in NG108-15 cells: AT2-receptor inhibits PKC alpha and p21ras activity
Endocrinology
147
4263-4272
2006
Mus musculus, Rattus norvegicus
Villanueva-Garcia, D.; Wang, K.T.; Nielsen, H.C.; Ramadurai, S.M.
Expression of specific protein kinase C (PKC) isoforms and ligand-specific activation of PKCalpha in late gestation fetal lung
Exp. Lung Res.
33
185-196
2007
Rattus norvegicus
Saraiva, L.; Silva, R.D.; Pereira, G.; Goncalves, J.; Corte-Real, M.
Specific modulation of apoptosis and Bcl-xL phosphorylation in yeast by distinct mammalian protein kinase C isoforms
J. Cell Sci.
119
3171-3181
2006
Mus musculus, Rattus norvegicus
Nawaratne, R.; Gray, A.; Jorgensen, C.H.; Downes, C.P.; Siddle, K.; Sethi, J.K.
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation
Mol. Endocrinol.
20
1838-1852
2006
Rattus norvegicus
Sampson, S.R.; Cooper, D.R.
Specific protein kinase C isoforms as transducers and modulators of insulin signaling
Mol. Genet. Metab.
89
32-47
2006
Homo sapiens, Mus musculus, Rattus norvegicus
Kim, J.Y.; Park, C.S.
Potentiation of large-conductance calcium-activated potassium (BK(Ca)) channels by a specific isoform of protein kinase C
Biochem. Biophys. Res. Commun.
365
459-465
2008
Rattus norvegicus
Fornes, A.; Nunez, E.; Alonso-Torres, P.; Aragon, C.; Lopez-Corcuera, B.
Trafficking properties and activity regulation of the neuronal glycine transporter GLYT2 by protein kinase C
Biochem. J.
412
495-506
2008
Rattus norvegicus
Lee, S.; Lynn, E.G.; Kim, J.A.; Quon, M.J.
Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling
Endocrinology
149
2451-2458
2008
Rattus norvegicus (P09217)
Waraich, R.S.; Weigert, C.; Kalbacher, H.; Hennige, A.M.; Lutz, S.Z.; Haering, H.U.; Schleicher, E.D.; Voelter, W.; Lehmann, R.
Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cells
J. Biol. Chem.
283
11226-11233
2008
Rattus norvegicus (P09215)
Dries, D.R.; Newton, A.C.
Kinetic analysis of the interaction of the C1 domain of protein kinase C with lipid membranes by stopped-flow spectroscopy
J. Biol. Chem.
283
7885-7893
2008
Rattus norvegicus
Weng, J.Y.; Hsu, T.T.; Sun, S.H.
Functional characterization of P2Y1 versus P2X receptors in RBA-2 astrocytes: elucidate the roles of ATP release and protein kinase C
J. Cell. Biochem.
104
554-567
2008
Rattus norvegicus
Jajoo, S.; Mukherjea, D.; Brewer, G.J.; Ramkumar, V.
Pertussis toxin B-oligomer suppresses human immunodeficiency virus-1 Tat-induced neuronal apoptosis through feedback inhibition of phospholipase C-beta by protein kinase C
Neuroscience
151
525-532
2008
Rattus norvegicus
Baldanzi, G.; Alchera, E.; Imarisio, C.; Gaggianesi, M.; Dal Ponte, C.; Nitti, M.; Domenicotti, C.; van Blitterswijk, W.J.; Albano, E.; Graziani, A.; Carini, R.
Negative regulation of diacylglycerol kinase theta mediates adenosine-dependent hepatocyte preconditioning
Cell Death Differ.
17
1059-1068
2010
Rattus norvegicus
Kwak, H.J.; Park, K.M.; Choi, H.E.; Lim, H.J.; Park, J.H.; Park, H.Y.
The cardioprotective effects of zileuton, a 5-lipoxygenase inhibitor, are mediated by COX-2 via activation of PKC delta
Cell. Signal.
22
80-87
2010
Rattus norvegicus
Nakamura, K.; Yokotani, K.
Presynaptic BK type Ca(2+)-activated K(+) channels are involved in prostanoid TP receptor-mediated inhibition of noradrenaline release from the rat gastric sympathetic nerves
Eur. J. Pharmacol.
629
111-117
2010
Rattus norvegicus
Hansson, M.J.; Morota, S.; Teilum, M.; Mattiasson, G.; Uchino, H.; Elmer, E.
Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume
J. Biol. Chem.
285
741-750
2010
Rattus norvegicus
Parrales, A.; Palma-Nicolas, J.P.; Lopez, E.; Lopez-Colome, A.M.
Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression
J. Cell. Physiol.
222
302-312
2010
Rattus norvegicus
Jiang, H.; Cheng, D.; Liu, W.; Peng, J.; Feng, J.
Protein kinase C inhibits autophagy and phosphorylates LC3
Biochem. Biophys. Res. Commun.
395
471-476
2010
Rattus norvegicus
Leonard, T.A.; Rozycki, B.; Saidi, L.F.; Hummer, G.; Hurley, J.H.
Crystal structure and allosteric activation of protein kinase C betaII
Cell
144
55-66
2011
Rattus norvegicus
Martin, T.D.; Mitin, N.; Cox, A.D.; Yeh, J.J.; Der, C.J.
Phosphorylation by protein kinase Calpha regulates RalB small GTPase protein activation, subcellular localization, and effector utilization
J. Biol. Chem.
287
14827-14836
2012
Rattus norvegicus
Vargas-Lopes, C.; Madeira, C.; Kahn, S.A.; Albino do Couto, I.; Bado, P.; Houzel, J.C.; De Miranda, J.; de Freitas, M.S.; Ferreira, S.T.; Panizzutti, R.
Protein kinase C activity regulates D-serine availability in the brain
J. Neurochem.
116
281-290
2011
Rattus norvegicus
Williams, A.D.; Jung, S.; Poolos, N.P.
Protein kinase C bidirectionally modulates Ih and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons
J. Physiol.
593
2779-2792
2015
Rattus norvegicus
Cole, T.R.; Igumenova, T.I.
Expression and purification of the N-terminal regulatory domain of protein kinase C for biophysical studies
Protein Expr. Purif.
110
14-21
2015
Rattus norvegicus