Literature summary for 2.7.11.13 extracted from

Parrales, A.; Palma-Nicolas, J.P.; Lopez, E.; Lopez-Colome, A.M.
Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression (2010), J. Cell. Physiol., 222, 302-312.

Search for more literature for 2.7.11.13

Inhibitors

Inhibitors	Comment	Organism	Structure
Ro-32-0432	conventional PKC inhibitor	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
retinal pigment epithelial cell	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + insulin receptor substrate-1	-	Rattus norvegicus	ADP + phosphorylated insulin receptor substrate-1	-	?
additional information	thrombin-induced cyclin D1expression requires the activation of conventional PKC isoforms	Rattus norvegicus	?	-	?

Synonyms

Synonyms	Comment	Organism
PKC	-	Rattus norvegicus
PKCalpha	isoform	Rattus norvegicus
PKCbetaI	isoform	Rattus norvegicus
PKCbetaII	isoform	Rattus norvegicus
PKCgamma	isoform	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Rattus norvegicus

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Release 2023.1 (January 2023)