Reference on EC 2.4.1.149 - N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
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Van den Eijnden, D.H.; Winterwerp, H.; Smeeman, P.; Schiphorst, W.E.C.M.
Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1-3 and beta 1-6 N-acetylglucosaminyltransferase activity
J. Biol. Chem.
258
3435-3437
1983
Rattus norvegicus
Zielenski, J.; Koscielak, J.
The occurrence of two novel N-acetylglucosaminyltransferase activities in human serum
FEBS Lett.
158
164-168
1983
Homo sapiens
Hosomi, O.; Takeya, A.; Kogure, T.
Human serum contains N-acetyllactosamine: beta 1-3 N-acetylglucosaminyltransferase activity
J. Biochem.
95
1655-1659
1984
Homo sapiens
Holmes, E.H.
Characterization of a beta 1-->3-N-acetylglucosaminyltransferase associated with synthesis of type 1 and type 2 lacto-series tumor-associated antigens from the human colonic adenocarcinoma cell line SW403
Arch. Biochem. Biophys.
260
461-468
1988
Homo sapiens
van den Eijnden, D.H.; Koenderman, A.H.L.; Schiphorst, W.E.C.M.
Biosynthesis of blood group i-active polylactosaminoglycans. Partial purification and properties of an UDP-GlcNAc:N-acetyllactosaminide beta 1-->3-N-acetylglucosaminyltransferase from Novikoff tumor cell ascites fluid
J. Biol. Chem.
263
12461-12471
1988
Rattus norvegicus
Kawashima, H.; Yamamoto, K.; Osawa, T.; Irimura, T.
Purification and characterization of UDP-GlcNAc:Galbeta 1-4Glc(NAc)beta-1,3-N-acetylglucosaminyltransferase (poly-N-acetyllactosamine extension enzyme) from calf serum
J. Biol. Chem.
268
27118-27126
1993
Bos taurus
McAuliffe, J.C.; Ujita, M.; Fukuda, M.; Hindsgaul, O.
Synthesis of selectively radiolabeled hexasaccharides for the determination of enzymatic regioselectivity
Glycoconjugate J.
16
767-772
1999
Homo sapiens
Fukuzumi, M.; Maruyama, S.; Sano, M.; Fukui, S.
Comparison of the expression of cell surface poly-N-acetyllactosamine-type oligosaccharides in PC12 cells with those in its variant PC12D
Glycobiology
11
481-494
2001
Rattus norvegicus
Kataoka, K.; Huh, N.h.
A novel beta1,3-N-acetylglucosaminyltransferase involved in invasion of cancer cells as assayed in vitro
Biochem. Biophys. Res. Commun.
294
843-848
2002
Mus musculus (Q8K0J2), Mus musculus, Homo sapiens (Q8NFL0), Homo sapiens, Mus musculus beta3GnT7 (Q8K0J2)
Sasaki, K.; Kurata-Miura, K.; Ujita, M.; Angata, K.; Nakagawa, S.; Sekine, S.; Nishi, T.; Fukuda, M.
Expression cloning of cDNA encoding a human beta-1,3-N-acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis
Proc. Natl. Acad. Sci. USA
94
14294-14299
1997
Homo sapiens (O43505)
Salo, H.; Aitio, O.; Ilves, K.; Bencomo, E.; Toivonen, S.; Penttil, L.; Niemel, R.; Salminen, H.; Grabenhorst, E.; Renkonen, R.; Renkonen, O.
Several polylactosamine-modifying glycosyltransferases also use internal GalNAcbeta1-4GlcNAc units of synthetic saccharides as acceptors
Glycobiology
12
217-228
2002
Homo sapiens
Hummel, M.; Hedrich, H.C.; Hasilik, A.
Elongation of N-acetyllactosamine repeats in diantennary oligosaccharides
Eur. J. Biochem.
245
428-433
1997
Cricetulus griseus
Basu, M.; Basu, S.
Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by beta1-3- and beta1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma
J. Biol. Chem.
259
12557-12562
1984
Mus musculus
Seko, A.; Yamashita, K.
beta1,3-N-Acetylglucosaminyltransferase-7 (beta3Gn-T7) acts efficiently on keratan sulfate-related glycans
FEBS Lett.
556
216-220
2004
Homo sapiens
Biellmann, F.; Henion, T.R.; Burki, K.; Hennet, T.
Impaired sexual behavior in male mice deficient for the beta 1-3 N-acetylglucosaminyltransferase-I gene
Mol. Reprod. Dev.
75
699-706
2008
BRENDA: Mus musculus
Textmining: Mus sp.
Lee, P.L.; Kohler, J.J.; Pfeffer, S.R.
Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis
Glycobiology
19
655-664
2009
Homo sapiens
Bao, X.; Kobayashi, M.; Hatakeyama, S.; Angata, K.; Gullberg, D.; Nakayama, J.; Fukuda, M.; Fukuda, M.
Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase
Proc. Natl. Acad. Sci. USA
106
12109-12114
2009
Homo sapiens
Peng, W.; Pranskevich, J.; Nycholat, C.; Gilbert, M.; Wakarchuk, W.; Paulson, J.C.; Razi, N.
Helicobacter pylori beta1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans
Glycobiology
22
1453-1464
2012
Helicobacter pylori
Gao, L.; Zhang, H.; Zhang, B.; Zhu, J.; Chen, C.; Liu, W.
B3GNT3 overexpression is associated with unfavourable survival in non-small cell lung cancer
J. Clin. Pathol.
71
642-647
2018
Homo sapiens (Q9Y2A9), Homo sapiens
Stults, CL; Macher, BA
Beta 1-3-N-acetylglucosaminyltransferase in human leukocytes: properties and role in regulating neolacto glycosphingolipid biosynthesis.
Arch Biochem Biophys
303
125-33
1993
Homo sapiens
Tian, G; Li, G; Liu, P; Wang, Z; Li, N
Glycolysis-Based Genes Associated with the Clinical Outcome of Pancreatic Ductal Adenocarcinoma Identified by The Cancer Genome Atlas Data Analysis.
DNA Cell Biol
39
417-427
2020
Homo sapiens
Zhou, D; Dinter, A; Gutiérrez Gallego, R; Kamerling, JP; Vliegenthart, JF; Berger, EG; Hennet, T
A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases.
Proc Natl Acad Sci U S A
96
406-11
1999
Homo sapiens, Mus musculus
Henion, TR; Raitcheva, D; Grosholz, R; Biellmann, F; Skarnes, WC; Hennet, T; Schwarting, GA
Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons.
J Neurosci
25
1894-903
2005
Mus sp.
Shaheen, R; Faqeih, E; Ansari, S; Alkuraya, FS
A truncating mutation in B3GNT1 causes severe Walker-Warburg syndrome.
Neurogenetics
2013
insertion sequences
Ho, WL; Che, MI; Chou, CH; Chang, HH; Jeng, YM; Hsu, WM; Lin, KH; Huang, MC
B3GNT3 expression suppresses cell migration and invasion and predicts favorable outcomes in neuroblastoma.
Cancer Sci
104
1600-8
2013
Homo sapiens
Zhang, W; Hou, T; Niu, C; Song, L; Zhang, Y
B3GNT3 Expression Is a Novel Marker Correlated with Pelvic Lymph Node Metastasis and Poor Clinical Outcome in Early-Stage Cervical Cancer.
PLoS One
10
e0144360
2015
Homo sapiens, Human papillomavirus, Indicator
Sun, Y; Liu, T; Xian, L; Liu, W; Liu, J; Zhou, H
B3GNT3, a Direct Target of miR-149-5p, Promotes Lung Cancer Development and Indicates Poor Prognosis of Lung Cancer.
Cancer Manag Res
12
2381-2391
2020
Homo sapiens
Wang, JS; Ruan, F; Guo, LZ; Wang, FG; Wang, FL; An, HM
B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers.
Genes Genomics
43
447-457
2021
Homo sapiens
Leng, X; Wei, S; Mei, J; Deng, S; Yang, Z; Liu, Z; Guo, C; Deng, Y; Xia, L; Cheng, J; Zhao, K; Gan, F; Li, C; Merrell, KW; Molina, JR; Metro, G; Liu, L
Identifying the prognostic significance of B3GNT3 with PD-L1 expression in lung adenocarcinoma.
Transl Lung Cancer Res
10
965-980
2021
Homo sapiens
Buysse, K; Riemersma, M; Powell, G; van Reeuwijk, J; Chitayat, D; Roscioli, T; Kamsteeg, EJ; van den Elzen, C; van Beusekom, E; Blaser, S; Babul-Hirji, R; Halliday, W; Wright, GJ; Stemple, DL; Lin, YY; Lefeber, DJ; van Bokhoven, H
Missense mutations in ?-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome.
Hum Mol Genet
2013
Danio rerio, Homo sapiens
Veerman, K; Tardiveau, C; Martins, F; Coudert, J; Girard, JP
Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes.
Cell Rep
26
3116-3131.e5
2019
porcine hemagglutinating encephalomyelitis virus
Kitayama, K; Hayashida, Y; Nishida, K; Akama, TO
Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans.
J Biol Chem
282
30085-96
2007
Homo sapiens
Wright, KM; Lyon, KA; Leung, H; Leahy, DJ; Ma, L; Ginty, DD
Dystroglycan organizes axon guidance cue localization and axonal pathfinding.
Neuron
76
931-44
2012
Mus musculus, Mus sp.
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