Information on EC 1.18.1.2 - ferredoxin-NADP+ reductase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY hide
1.18.1.2
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RECOMMENDED NAME
GeneOntology No.
ferredoxin-NADP+ reductase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
photosynthesis light reactions
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ubiquinol-6 biosynthesis from 4-aminobenzoate (eukaryotic)
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photosynthesis
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Photosynthesis
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Metabolic pathways
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SYSTEMATIC NAME
IUBMB Comments
ferredoxin:NADP+ oxidoreductase
A flavoprotein (FAD). In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe-2S] ferredoxins, but in other bacteria it can also reduce bacterial [4Fe-4S] ferredoxins and flavodoxin.
CAS REGISTRY NUMBER
COMMENTARY hide
56367-57-8
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9029-33-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain 7119, multiple forms: FNR-I, FNR-II, FNR-III, FNR-IV
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Manually annotated by BRENDA team
animal
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain IAM M-135, cyanobacterium
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
marine green algae
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain CT1512
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
single copy FNR
UniProt
Manually annotated by BRENDA team
strain RK-1, red alga
Uniprot
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
denitrifying bacterium
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Automatic Mining of ENzyme DAta
cyanobacterium strain 7119
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1004263 A+, 1013164 A+, 1013714 A+, 1020280 A+, 1023826 A+, 1031980 A+, 1046145 A+, 1050640 A+, 1058271 A+, 1085530 A+, 1197020 A+, 1197274 A+, 1236879 A+, 1237285 A+, 1238887 A+, 1239080 A+, 1239237 A+, 1249669 A+, 1335465 A+, 1335943 A+, 1375975 A+, 1426199 A+, 1488509 A+, 1618135 A+, 1643442 A+, 1677894 A+, 1678047 A+, 1678792 A+, 1678793 A+, 1678802 A+, 1678815 A+, 1678817 A+, 1678819 A+, 1678861 A+, 1678867 A+, 1678868 A+, 1678869 A+, 1678875 A+, 1678880 A+, 1678907 A+, 1678918 A+, 1678942 A+, 1678944 A+, 1678950 A+, 1678954 A+, 1678990 A+, 1678994 A+, 1679011 A+, 1679013 A+, 1679017 A+, 1679038 A+, 1679040 A+, 1679042 A+, 1679056 A+, 1679073 A+, 1679087 A+, 1679091 A+, 1679092 A+, 1679099 A+, 1679104 A+, 1679105 A+, 1679107 A+, 1679135 A+, 1679156 A+, 1679158 A+, 1679161 A+, 1679173 A+, 1679178 A+, 1679179 A+, 1679212 A+, 1679222 A+, 1679244 A+, 1679261 A+, 1679272 A+, 1679278 A+, 1679293 A+, 1679304 A+, 1679310 A+, 1679328 A+, 1679329 A+, 1679331 A+, 1679337 A+, 1679338 A+, 1679346 A+, 1679378 A+, 1679379 A+, 2236672 A+, 2236690 A+, 2236718 A+, 2237323 A+, 2237383 A+, 2237409 A+, 2237421 A+, 2237428 A+, 2237437 A+, 2237447 A+, 2237449 A+, 2237454 A+, 2250469 A+, 2253160 A+, 2266416 A+, 2268414 A+, 2369365 A+, 2398865 A+, 2400139 A+, 2400277 A+, 2409291 A+, 2470985 A+, 2512762 A+, 2611499 A+, 2746654 A+, 2746669 A+, 2746670 A+, 2746696 A+, 2746717 A+, 2746730 A+, 2746734 A+, 2746738 A+, 2746751 A+, 2746753 A+, 2746773 A+, 2746778 A+, 2746782 A+, 2746796 A+, 2746842 A+, 285407 A+, 285541 A+, 392930 A+, 392933 A+, 394419 A+, 394426 A+, 395075 A+, 437695 A+, 644783 A+, 644786 A+, 644788 A+, 645611 A+, 654561 A+, 655625 A+, 658019 A+, 659035 A+, 659425 A+, 660065 A+, 661234 A+, 666010 A+, 671644 A+, 676081 A+, 677038 A+, 686702 A+, 689391 A+, 697331 A+, 715756 A+, 716444 A+, 716762 A+, 721456 A+, 721788 A+, 723784 A+, 724894 A+, 725315 A+, 725783 A+, 727542 A+, 728513 A+, 728618 A+, 738123 A+, 985163 A+, 986184 A+, 986227 A+, 986247 A+, 986248 A+, 986300 A+, 986302 A+, 986313 A+, 986326 A+, 986358 A+, 986359 A+, 986409 A+, 986467 A+, 986474 A+, 986480 A+, 986493 A+, 986523 A+, 986555 A+, 986557 A+, 986567 A+, 986575 A+, 986580 A+, 986599 A+, 986601 A+, 986607 A+, 986612 A+, 986621 A+, 986626 A+, 986628 A+, 986631 A+, 986632 A+, 986648 A+, 986653 A+, 1013961 A++, 1081664 A++, 1677898 A++, 1677905 A++, 1678785 A++, 1678834 A++, 1678845 A++, 1678860 A++, 1678878 A++, 1678900 A++, 1678922 A++, 1678939 A++, 1678984 A++, 1679086 A++, 1679163 A++, 1679355 A++, 2236430 A++, 2236657 A++, 2236682 A++, 2236698 A++, 2237312 A++, 2237316 A++, 2237339 A++, 2237342 A++, 2237347 A++, 2237400 A++, 2237416 A++, 2237431 A++, 2237439 A++, 2247904 A++, 2612152 A++, 2745741 A++, 2745987 A++, 2746099 A++, 2746692 A++, 2746705 A++, 2746709 A++, 2746712 A++, 285526 A++, 285543 A++, 285549 A++, 285550 A++, 394400 A++, 657646 A++, 657824 A++, 658076 A++, 658611 A++, 658714 A++, 660092 A++, 671116 A++, 671963 A++, 673607 A++, 676631 A++, 681373 A++, 688312 A++, 697907 A++, 698606 A++, 701121 A++, 716461 A++, 718957 A++, 719398 A++, 719751 A++, 985134 A++, 985217 A++, 985322 A++, 985428 A++, 985460 A++, 985491 A++, 986180 A++, 986186 A++, 986218 A++, 986233 A++, 986252 A++, 986258 A++, 986301 A++, 986327 A++, 986351 A++, 986412 A++, 986419 A++, 986436 A++, 986450 A++, 986454 A++, 986468 A++, 986479 A++, 986487 A++, 986492 A++, 986506 A++, 1251037 A++, 1677516 A++, 1677937 A++, 1678080 A++, 1678786 A++, 1678791 A++, 1678824 A++, 1678862 A++, 1678863 A++, 1678946 A++, 1678952 A++, 1678961 A++, 1678989 A++, 1679024 A++, 1679080 A++, 1679085 A++, 2102344 A++, 2236743 A++, 2236749 A++, 2237313 A++, 2237318 A++, 2237320 A++, 2237322 A++, 2237324 A++, 2237331 A++, 2237332 A++, 2237333 A++, 2237351 A++, 2237358 A++, 2237360 A++, 2237362 A++, 2237364 A++, 2237368 A++, 2237369 A++, 2248939 A++, 2395769 A++, 2400164 A++, 2400831 A++, 2409541 A++, 2746664 A++, 2746701 A++, 285502 A++, 285524 A++, 285525 A++, 285534 A++, 285536 A++, 285542 A++, 437705 A++, 657696 A++, 658617 A++, 658706 A++, 659284 A++, 671585 A++, 671974 A++, 673487 A++, 674373 A++, 675830 A++, 689530 A++, 697998 A++, 700751 A++, 701126 A++, 719752 A++, 719777 A++, 728563 A++, 985300 A++, 985410 A++, 986210 A++, 986309 A++, 986332 A++, 986361 A++, 986369 A++, 986405 A++, 986426 A++, 986434 A++, 986447 A++, 986451 A++, 986484 A++, 986500 A++, 986501 A++, 986508 A++, 986556 A++, 986620 A++, 986654 A++, 644787 A+++, 658287 A+++, 675349 A+++, 675839 A+++, 714174 A+++, 986178 A+++, 986245 A+++, 986307 A+++, 986338 A+++, 986371 A+++, 986390 A+++, 986422 A+++, 986471 A+++, 986530 A+++, 986571 A+++, 986590 A+++, 986596 A+++, 986619 A+++, 986647 A+++, 285498 A++++, 285499 A++++, 285510 A++++, 285530 A++++, 285545 A++++, 659483 A++++, 696232 A++++, 720222 A++++, 986200 A++++, 986246 A++++, 986264 A++++, 986311 A++++, 986337 A++++, 986387 A++++, 986406 A++++, 986432 A++++, 986458 A++++, 986478 A++++, 986488 A++++, 986510 A++++, 986569 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
chick
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Uniprot
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Nostoc sp. ATCC 29151
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UniProt
Manually annotated by BRENDA team
strain MAC, cyanobacterium
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
protozoa
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain 37b4
SwissProt
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
rumen bacterium
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain Atlanta
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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SwissProt
Manually annotated by BRENDA team
i.e. Thermosynechococcus elongatus, single copy gene petH
SwissProt
Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
trout
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
yeasts
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Automatic Mining of ENzyme DAta
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,4-benzoquinone + NADP+
? + NADPH + H+
show the reaction diagram
1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
1,8-dihydroxy-9,10-anthraquinone + NADP+
? + NADPH + H+
show the reaction diagram
2 ferricyanide + NAD(P)H
2 ferrocyanide + NAD(P)+ + H+
show the reaction diagram
2 ferricyanide + NADH
2 ferrocyanide + NAD+ + H+
show the reaction diagram
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?
2 ferricyanide + NADPH
2 ferrocyanide + NADP+ + H+
show the reaction diagram
2 ferricytochrome c2 + NADPH
2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
2 ferrocytochrome c + NAD+ + H+
2 ferricytochrome c + NADH
show the reaction diagram
2 oxidized ferredoxin + NADH + H+
2 reduced ferredoxin + NAD+
show the reaction diagram
2 oxidized ferredoxin + NADPH + H+
2 reduced ferredoxin + NADP+
show the reaction diagram
2 reduced ferredoxin + NAD+
2 oxidized ferredoxin + NADH + H+
show the reaction diagram
NAD+ is a poor substrate
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?
2 reduced ferredoxin + NADP+
2 oxidized ferredoxin + NADPH + H+
show the reaction diagram
2 reduced ferricyanide + NADP+
2 oxidized ferricyanide + NADPH
show the reaction diagram
2,3-dichloro-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
2,3-diglutathionyl-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
2,5-dimethyl-1,4-benzoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.07 V
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?
2,6-dichlorophenolindophenol + NADH
NAD+ + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
2,6-dichlorophenolindophenol + NADP+
reduced 2,6-dichlorophenolindophenol + NADPH
show the reaction diagram
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diaphorase activity
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?
2,6-dichlorophenolindophenol + NADPH + H+
?
show the reaction diagram
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?
2,6-dichlorophenolindophenol + NADPH + H+
reduced 2,6-dichlorophenolindophenol + NADP+
show the reaction diagram
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?
2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride + NADPH
?
show the reaction diagram
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?
2-(p-iodophenyl)-3-(p-nitrophenyl)-5-phenyltetrazolium chloride + NADPH
? + NADP+
show the reaction diagram
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?
2-hydroxy-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.41 V
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?
2-methyl-1,4-benzoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential 0.01 V
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?
2-methyl-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.20 V
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?
2-methyl-3-glutathionyl-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.16 V
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?
2-methyl-3-hydroxy-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.46 V
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?
2-methyl-5-hydroxy-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.16 V
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?
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide + NADPH + H+
? + NADP+
show the reaction diagram
5,8-dihydroxy-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.11 V
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?
5-hydroxy-1,4-naphthoquinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.09 V
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?
9,10-phenanthrenequinone + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.12 V
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?
aclacinomycin A + NADP+
7-deoxyaklavinone + NADPH
show the reaction diagram
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under anaerobic conditions
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?
cytochrome c + NADPH + H+
?
show the reaction diagram
weakest substrate
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?
daunomycin + NADP+
7-deoxydaunomycinone + NADPH
show the reaction diagram
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under anaerobic conditions
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?
daunorubicin + NADP+
? + NADPH + H+
show the reaction diagram
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single electron reduction potential -0.34 V
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?
dibromothymoquinone + NADPH
? + NADP+
show the reaction diagram
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diaphorase activity, no direct involvement of thiol or amino groups in the reaction
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?
dibromothymoquinone + NADPH
reduced dibromothymoquinone + NADP+
show the reaction diagram
FAD + NADPH + H+
reduced FAD + NADP+
show the reaction diagram
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