6.5.1.8: 3'-phosphate/5'-hydroxy nucleic acid ligase

This is an abbreviated version, for detailed information about 3'-phosphate/5'-hydroxy nucleic acid ligase, go to the full flat file.

Reaction

(ribonucleotide)n-2',3'-cyclophosphate
+
5'-hydroxy-(ribonucleotide)m
+
GTP
+
H2O
=
(ribonucleotide)n+m
+
GMP
+
diphosphate

Synonyms

3'-P RNL, MXAN_0280, MXAN_4982, RNA-splicing ligase, rtcB, Rtcb-1, RtcB1, tRNA-splicing ligase

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase