6.3.5.9: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)

This is an abbreviated version!
For detailed information about hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing), go to the full flat file.

Reaction

2 ATP +

+ 2 L-glutamine + 2 H2O =

+ 2 phosphate +

+ 2 L-glutamate

Synonyms

CbiA, cobalamin biosynthesis aminotransferase, CobB, cobyric acid synthase, cobyrinic acid a,c-diamide synthase, new NaMN:Me2Bza phosphoribosyltransferase enzyme

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
6116	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
1	General Stability
28	KM Value [mM]
2	Metals/Ions
10	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organism
5	Pathway
4	pH Optimum
1	pI Value
6	Protein Variants
3	Purification (Commentary)
1	Reaction
9	Reference
2	Specific Activity [micromol/min/mg]
3	Storage Stability
36	Substrates and Products (Substrate)
7	Subunits
15	Synonyms
1	Systematic Name
8	Turnover Number [1/s]

Natural Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Natural Substrates Products on EC 6.3.5.9 - hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Natural Substrate Search

5'-deoxy-5'-adenosyl-cobyrinic acid + 2 ATP + 2 glutamine + 2 H2O

5'-deoxy-5'-adenosyl-cobyrinic acid ac-diamide + 2 ADP + 2 phosphate + 2 glutamate

Pseudomonas denitrificans (nom. rej.)

cobalamin biosynthetic pathway

651618

ATP + cobyrinic acid + L-glutamine + H2O

ADP + phosphate + cobyrinic acid a,c-diamide + L-glutamate

Pseudomonas denitrificans (nom. rej.)

P21632

cobalamin pathway from cobyrinic acid

644524

ATP + hydrogenobyrinic acid + L-glutamine + H2O

ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate

2 entries

additional information

4 entries