6.3.1.8: glutathionylspermidine synthase

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For detailed information about glutathionylspermidine synthase, go to the full flat file.

Reaction

Synonyms

bifunctional glutathionylspermidine synthetase/amidase, Gen Bank AE000381-derived protein GI 1789361, GenBank U66520-derived protein GI 1813514, Glutathione:spermidine ligase (ADP-forming), Glutathione:spermidine ligase [ADP-forming], glutathionylspermidine synthetase, Glutathionylspermidine synthetase (Crithidia fasciculata strain HS6 gene Cf-GSS), Glutathionylspermidine synthetase (Crithidia fasciculata), Glutathionylspermidine synthetase/amidase, Gsp synthetase, GspS, GspSA, LiGSPS, Protein (Escherichia coli strain K12-MG1655 gene gsp), Synthetase, glutathionylspermidine, Synthetase, glutathionylspermidine (Crithidia fasciculata fragment), Synthetase, glutathionylspermidine (Crithidia fasciculata strain HS6 gene Cf-GSS), Synthetase, glutathionylspermidine (Crithidia fasciculata), Synthetase, glutathionylspermidine (Escherichia coli clone pJBM1 gene gsp), TryS

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.1 Acid—ammonia (or amine) ligases (amide synthases)

                6.3.1.8 glutathionylspermidine synthase

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Results	in table
578	AA Sequence
4	Application
5	CAS Registry Number
12	Cloned(Commentary)
7	Cofactor
2	Crystallization (Commentary)
4	General Information
1	IC50 Value
37	Inhibitors
8	Ki Value [mM]
41	KM Value [mM]
1	Localization
7	Metals/Ions
9	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
25	Organism
5	Pathway
15	PDB ID
5	pH Optimum
1	pH Range
1	pI Value
15	Protein Variants
10	Purification (Commentary)
5	Reaction
1	Reaction Type
23	Reference
1	Renatured (Commentary)
2	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
5	Subunits
31	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
10	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

9.2

gamma-Glu-L-Cys(S-butyl)-Gly

Crithidia fasciculata

-

-

966

11.3

gamma-Glu-L-Cys(S-ethyl)-Gly

Crithidia fasciculata

-

-

966

8.7

gamma-Glu-L-Cys(S-propyl)-Gly

Crithidia fasciculata

-

-

966

2.5

gamma-L-Glu-L-Ala-Gly

Crithidia fasciculata

-

-

966

8.8

gamma-L-Glu-L-Cys(S-methyl)-Gly

Crithidia fasciculata

-

-

966

15

gamma-L-Glu-L-Cys-Gly

Crithidia fasciculata

-

-

966

10

gamma-L-Glu-L-Ile-Gly

Crithidia fasciculata

-

-

966

11.8

gamma-L-Glu-L-Val-Gly

Crithidia fasciculata

-

-

966

4.2

spermidine

Crithidia fasciculata

P90518, Q5DM89

pH 7.2, 25°C, recombinant trypanothione synthase performing the glutathionylspermidine synthase reaction

662446

additional information

additional information

Crithidia fasciculata

-

-

964

-