5.3.2.1: phenylpyruvate tautomerase
This is an abbreviated version!
For detailed information about phenylpyruvate tautomerase, go to the full flat file.
Word Map on EC 5.3.2.1
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5.3.2.1
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necrosis
-
monocyte
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tnf
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endothelial
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lymphocyte
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chemokine
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autoimmune
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anti-mif
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glucocorticoid
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arthritis
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pulmonary
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artery
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leukocyte
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angiogenesis
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sepsis
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rheumatoid
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tnf-alpha
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lipopolysaccharide
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factor-alpha
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myocardial
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t-cells
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atherosclerosis
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chemotactic
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c-reactive
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pituitary
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chemoattractant
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infarct
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lupus
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lymphokine
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toll-like
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autocrine
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cxcr2
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synovial
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ifn-gamma
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il-1beta
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counter-regulator
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chemokine-like
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erythematosus
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immunoregulatory
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cell-mediated
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glomerulonephritis
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dehalogenation
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tautomerization
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counterregulates
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delayed-type
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pro-tumorigenic
-
drug development
- 5.3.2.1
- necrosis
- monocyte
- tnf
- endothelial
- lymphocyte
- chemokine
- autoimmune
-
anti-mif
- glucocorticoid
- arthritis
- pulmonary
- artery
- leukocyte
- angiogenesis
- sepsis
-
rheumatoid
- tnf-alpha
- lipopolysaccharide
- factor-alpha
- myocardial
- t-cells
- atherosclerosis
-
chemotactic
-
c-reactive
- pituitary
-
chemoattractant
- infarct
-
lupus
- lymphokine
-
toll-like
-
autocrine
- cxcr2
-
synovial
- ifn-gamma
- il-1beta
-
counter-regulator
-
chemokine-like
- erythematosus
-
immunoregulatory
-
cell-mediated
- glomerulonephritis
-
dehalogenation
-
tautomerization
-
counterregulates
-
delayed-type
-
pro-tumorigenic
- drug development
Reaction
Synonyms
CaaD, CCH2, cis-3-chloroacrylic acid dehalogenase, cis-CaaD, Macrophage migration inhibitory factor, macrophage migration inhibitory factor tautomerase, MIF, MIF tautomerase, phenyl(enol)pyruvate tautomerase, Phenylpyruvate keto-enol tautomerase, Phenylpyruvic keto-enol isomerase, PPT, Tautomerase, phenylpyruvate, trans-3-chloroacrylic acid dehalogenase
ECTree
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IC50 Value
IC50 Value on EC 5.3.2.1 - phenylpyruvate tautomerase
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0.0062
(3Z)-3-[4-(dimethylamino)benzylidene]-7-hydroxy-2H-chromene-2,4(3H)-dione
Homo sapiens
-
-
0.007
(R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester
Homo sapiens
-
-
0.013
(S)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester
Homo sapiens
-
-
0.0015
3-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-7-hydroxy-2H-chromen-2-one
Homo sapiens
-
-
0.00028
7-hydroxy-3-[4-(2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]-2H-chromen-2-one
Homo sapiens
-
-
0.0005 - 0.002
caffeic acid
Bos taurus
-
IC50 ketonase reaction 0.5 microM, pH 6.5, room temperatur, IC50 enolase reaction 2.0 microM, pH 6.2, room temperatur
0.0209 - 0.2296
Cinnamic acid
Bos taurus
-
IC50 ketonase reaction 20.9 microM, pH 6.5, room temperatur, IC50 enolase reaction 229.6 microM, pH 6.2, room temperatur
0.0181 - 0.1033
p-coumaric acid
Bos taurus
-
IC50 ketonase reaction 18.1 microM, pH 6.5, room temperatur, IC50 enolase reaction 103.3 microM, pH 6.2, room temperatur
3.6241
parthenolide
Bos taurus
-
IC50 ketonase reaction 3624.1 microM, pH 6.5, room temperatur
0.0026 - 0.0195
umbelliferone
Bos taurus
-
IC50 ketonase reaction 2.6 microM, pH 6.5, room temperatur, IC50 enolase reaction 19.5 microM, pH 6.2, room temperatur
0.0155
Bos taurus
-
IC50 ketonase reaction 15.5 microM, pH 6.5, room temperatur
0.1158
carnosic acid
Bos taurus
-
IC50 enolase reaction 115.8 microM, pH 6.2, room temperatur
0.0076
Bos taurus
-
IC50 ketonase reaction 7.6 microM, pH 6.5, room temperatur
0.127
chlorogenic acid
Bos taurus
-
IC50 enolase reaction 127.0 microM, pH 6.2, room temperatur
10.3343
Ibuprofen
Bos taurus
-
IC50 ketonase reaction 10334.3 microM, pH 6.5, room temperatur
0.0878
Bos taurus
-
IC50 ketonase reaction 87.8 microM, pH 6.5, room temperatur
0.1757
o-coumaric acid
Bos taurus
-
IC50 enolase reaction 175.7 microM, pH 6.2, room temperatur
0.3766
Bos taurus
-
IC50 enolase reaction 376.6 microM, pH 6.2, room temperatur
7.1267
Phenylbutazone
Bos taurus
-
IC50 ketonase reaction 7126.7 microM, pH 6.5, room temperatur
0.0138
Bos taurus
-
IC50 ketonase reaction 13.8 microM, pH 6.5, room temperatur
0.0656
rosmarinic acid
Bos taurus
-
IC50 enolase reaction 65.6 microM, pH 6.2, room temperatur