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5.1.3.18: GDP-mannose 3,5-epimerase

This is an abbreviated version!
For detailed information about GDP-mannose 3,5-epimerase, go to the full flat file.

Word Map on EC 5.1.3.18

Reaction

GDP-alpha-D-mannose
=
GDP-beta-L-galactose

Synonyms

Epimerase, guanosine diphosphomannose, GDP-D-mannose 3'',5''-epimerase, GDP-D-mannose 3',5'-epimerase, GDP-D-mannose 3,5-epimerase, GDP-D-mannose-3',5'-epimerase, GDP-D-mannose:GDP-L-galactose epimerase, GDP-mannose 3",5"-epimerase, GDP-mannose 3',5'-epimerase, GDP-mannose-3',5'-epimerase, GME, GME1, GME2, OsGME

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.3 Acting on carbohydrates and derivatives
                5.1.3.18 GDP-mannose 3,5-epimerase

Crystallization

Crystallization on EC 5.1.3.18 - GDP-mannose 3,5-epimerase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
sitting drop vapor diffusion method, structures of complexes of the enzyme with GDP-alpha-D-mannose, GDP-beta-L-galactose and a mixture of GDP-beta-L-gulose. Structure of native wild-type enzyme in complex with GDP-D-mannose, native GME K178R, SeMet GME K178E, native GME Y174F in complex with GDP-L-galactose and native GME K217A in complex with GDP-D-mannose
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