5.1.3.18: GDP-mannose 3,5-epimerase
This is an abbreviated version!
For detailed information about GDP-mannose 3,5-epimerase, go to the full flat file.
Word Map on EC 5.1.3.18
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5.1.3.18
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ascorbate
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asa
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l-ascorbic
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tomato
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phosphorylase
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pyrophosphorylase
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l-galactose-1-phosphate
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l-galactono-1,4-lactone
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lycopersicum
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dehydroascorbate
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gpp
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epimerization
- 5.1.3.18
- ascorbate
- asa
-
l-ascorbic
- tomato
- phosphorylase
-
pyrophosphorylase
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l-galactose-1-phosphate
- l-galactono-1,4-lactone
- lycopersicum
- dehydroascorbate
- gpp
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epimerization
Reaction
Synonyms
Epimerase, guanosine diphosphomannose, GDP-D-mannose 3'',5''-epimerase, GDP-D-mannose 3',5'-epimerase, GDP-D-mannose 3,5-epimerase, GDP-D-mannose-3',5'-epimerase, GDP-D-mannose:GDP-L-galactose epimerase, GDP-mannose 3",5"-epimerase, GDP-mannose 3',5'-epimerase, GDP-mannose-3',5'-epimerase, GME, GME1, GME2, OsGME
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Reference
Reference on EC 5.1.3.18 - GDP-mannose 3,5-epimerase
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Barber, G.A.; Hebda, P.A.
GDP-D-mannose:GDP-L-galactose epimerase from Chlorella pyrenoidosa
Methods Enzymol.
83
522-525
1982
Auxenochlorella pyrenoidosa
Goudsmit, E.M.; Neufeld, E.F.
Formation of GDP-L-galactose from GDP-D-mannose
Biochem. Biophys. Res. Commun.
26
730-735
1967
Helix pomatia
Hebda, P.A.; Behrman, E.J.; Barber, G.A.
The guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase of Chlorella pyrenoidosa
Arch. Biochem. Biophys.
194
496-502
1979
Auxenochlorella pyrenoidosa
Barber, G.A.
Observations on the mechanism of the reversible epimerization of GDP-D-mannose to GDP-L-galactose by an enzyme from Chlorella pyrenoidosa
J. Biol. Chem.
254
7600-7603
1979
Auxenochlorella pyrenoidosa
Wolucka, B.A.; Davey, M.W.; Boerjan, W.
A high-performance liquid chromatography radio method for determination of L-ascorbic acid and guanosine 5'-diphosphate-L-galactose, key metabolites of the plant vitamin C pathway
Anal. Biochem.
294
161-168
2001
Arabidopsis thaliana
Wolucka, B.A.; Van Montagu, M.
GDP-mannose 3',5'-epimerase forms GDP-L-gulose, a putative intermediate for the de novo biosynthesis of vitamin C in plants
J. Biol. Chem.
278
47483-47490
2003
Arabidopsis thaliana
Wolucka, B.A.; Persiau, G.; Van Doorsselaere, J.; Davey, M.W.; Demol, H.; Vandekerckhove, J.; Van Montagu, M.; Zabeau, M.; Boerjan, W.
Partial purification and identification of GDP-mannose 3",5"-epimerase of Arabidopsis thaliana, a key enzyme of the plant vitamin C pathway
Proc. Natl. Acad. Sci. USA
98
14843-14848
2001
Arabidopsis thaliana (Q93VR3), Arabidopsis thaliana
Major, L.L.; Wolucka, B.A.; Naismith, J.H.
Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site
J. Am. Chem. Soc.
127
18309-18320
2005
Arabidopsis thaliana
Wolucka, B.A.; Goossens, A.; Inze, D.
Methyl jasmonate stimulates the de novo biosynthesis of vitamin C in plant cell suspensions
J. Exp. Bot.
56
527-2538
2005
Nicotiana tabacum
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Watanabe, K.; Suzuki, K.; Kitamura, S.
Characterization of a GDP-d-mannose 3'',5''-epimerase from rice
Phytochemistry
67
338-346
2006
Oryza sativa (A3C4S4), Oryza sativa
Gilbert, L.; Alhagdow, M.; Nunes-Nesi, A.; Quemener, B.; Guillon, F.; Bouchet, B.; Faurobert, M.; Gouble, B.; Page, D.; Garcia, V.; Petit, J.; Stevens, R.; Causse, M.; Fernie, A.R.; Lahaye, M.; Rothan, C.; Baldet, P.
GDP-D-mannose 3,5-epimerase (GME) plays a key role at the intersection of ascorbate and non-cellulosic cell-wall biosynthesis in tomato
Plant J.
60
499-508
2009
Solanum lycopersicum
Voxeur, A.; Gilbert, L.; Rihouey, C.; Driouich, A.; Rothan, C.; Baldet, P.; Lerouge, P.
Silencing of the GDP-D-mannose 3,5-epimerase affects the structure and cross-linking of the pectic polysaccharide rhamnogalacturonan II and plant growth in tomato
J. Biol. Chem.
286
8014-8020
2011
Solanum lycopersicum
Zhang, C.; Liu, J.; Zhang, Y.; Cai, X.; Gong, P.; Zhang, J.; Wang, T.; Li, H.; Ye, Z.
Overexpression of SlGMEs leads to ascorbate accumulation with enhanced oxidative stress, cold, and salt tolerance in tomato
Plant Cell Rep.
30
389-398
2011
Solanum lycopersicum (C6K2K9), Solanum lycopersicum (C6K2L0), Solanum lycopersicum
Yang, X.Y.; Xie, J.X.; Wang, F.F.; Zhong, J.; Liu, Y.Z.; Li, G.H.; Peng, S.A.
Comparison of ascorbate metabolism in fruits of two citrus species with obvious difference in ascorbate content in pulp
J. Plant Physiol.
168
2196-2205
2011
Citrus sinensis, Citrus unshiu (E9M5S1), Citrus unshiu
Li, J.; Cui, M.; Li, M.; Wang, X.; Liang, D.; Ma, F.
Expression pattern and promoter analysis of the gene encoding GDP-D-mannose 3',5'-epimerase under abiotic stresses and applications of hormones by kiwifruit
Sci. Hortic.
150
187-194
2013
Actinidia deliciosa (D3JYW9), Actinidia rufa (G1ETS7)
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Chen, Y.; Bu, J.; Zhao, Z.; Zhao, J.; Liu, M.
Cloning and expression analysis of GDP-mannose-3,5-epimerase (ZjGME) from Ziziphus jujuba Mill
Acta Hortic.
1116
49-53
2016
Ziziphus jujuba
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