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5.1.2.2: mandelate racemase

This is an abbreviated version!
For detailed information about mandelate racemase, go to the full flat file.

Word Map on EC 5.1.2.2

Reaction

(S)-Mandelate
=
(R)-mandelate

Synonyms

mandelate racemase, mandelic acid racemase, mdlA, MR, racemase, mandelate

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.2 Acting on hydroxy acids and derivatives
                5.1.2.2 mandelate racemase

KI Value

KI Value on EC 5.1.2.2 - mandelate racemase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
17.3 - 98
(R)-2-hydroxybutyrate
0.16 - 33
(R)-2-naphthylglycolate
0.95 - 3.3
(R)-atrolactate
32
(R)-lactate
pH 7.5, 25°C, recombinant wild-type enzyme
40.2
(R,S)-1-hydroxyethylphosphonate
pH 7.5, 25°C, recombinant wild-type enzyme
1.9
(R,S)-1-naphthylglycolate
25°C, pH 7.5
0.67
(R,S)-2,2,2-trifluoro-1-hydroxyethylphosphonate
pH 7.5, 25°C, recombinant wild-type enzyme
0.52
(R,S)-2-naphthylglycolate
25°C, pH 7.5
0.0047 - 0.238
(R,S)-alpha-hydroxybenzylphosphonate
5.1
(R,S)-methyl-alpha-hydroxybenzylphosphonate
-
-
11.4 - 71
(S)-2-hydroxybutyrate
0.48 - 5
(S)-2-naphthylglycolate
0.5
(S)-cyclohexylphenylglycolate
wild-type enzyme
26.1
(S)-lactate
pH 7.5, 25°C, recombinant wild-type enzyme
0.00591 - 1.41
1,1-diphenyl-1-hydroxymethylphosphonate
0.023 - 0.19
2-naphthohydroxamate
0.023 - 0.19
2-naphtholhydroxamate
0.027
3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)-propanoate
pH 7.5, 25°C, recombinant wild-type enzyme
1.3
3-Fluoropyruvate
pH and temperature not specified in the publication
5.5
alpha-hydroxyisobutyrate
pH 7.5, 25°C, recombinant wild-type enzyme
0.67 - 45
benzilate
0.0117 - 0.216
benzohydroxamate
0.0093
benzohydroxamic acid
-
-
0.65
benzoylformate
-
-
0.3
benzoylphosphonate
-
-
3.5
benzylphosphonate
-
-
0.00267
Cupferron
-
-
4.5
diphenylacetate
wild-type enzyme
1.8
mesoxalate
pH and temperature not specified in the publication
0.00279
N-hydroxyformanilide
-
-
0.2
phenylacetate
-
-
1.8
Tartronate
pH 7.5, 25°C, recombinant wild-type enzyme