4.4.1.22: S-(hydroxymethyl)glutathione synthase
This is an abbreviated version!
For detailed information about S-(hydroxymethyl)glutathione synthase, go to the full flat file.
Word Map on EC 4.4.1.22
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4.4.1.22
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1.2.1.1
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s-hydroxymethylglutathione
-
nad+
-
dehydrogenases
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gfa
-
paracoccus
-
methanol
-
denitrificans
-
methylotrophic
-
boidinii
- 4.4.1.22
-
1.2.1.1
- s-hydroxymethylglutathione
- nad+
- dehydrogenases
- gfa
-
paracoccus
- methanol
- denitrificans
-
methylotrophic
- boidinii
Reaction
Synonyms
EC 1.2.1.1, Gfa, glutathione-dependent formaldehyde-activating enzyme
ECTree
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Systematic Name
Systematic Name on EC 4.4.1.22 - S-(hydroxymethyl)glutathione synthase
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S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)
The enzyme from Paracoccus denitrificans accelerates the spontaneous reaction in which the adduct of formaldehyde and glutathione is formed, i.e. the substrate for EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase, in the formaldehyde-detoxification pathway.