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4.3.1.B2: imidazole glycerol phosphate synthase

This is an abbreviated version!
For detailed information about imidazole glycerol phosphate synthase, go to the full flat file.

Word Map on EC 4.3.1.B2

Reaction

L-glutamine
+
H2O
=
L-glutamate
+
NH3

Synonyms

HIS7, IGP synthase, IGPS, ImGP synthase

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.B2 imidazole glycerol phosphate synthase

Reaction

Reaction on EC 4.3.1.B2 - imidazole glycerol phosphate synthase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-glutamine + H2O = L-glutamate + NH3
show the reaction diagram
N1-[(5'-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamido-1-beta-D-ribofuranosyl 5'-phosphate + L-glutamine = L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
show the reaction diagram
N1-[(5'-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamido-1-beta-D-ribofuranosyl 5'-phosphate + NH3 = D-erythro-1-(imidazol-4-yl)glycerol phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
show the reaction diagram