4.3.1.B2: imidazole glycerol phosphate synthase
This is an abbreviated version!
For detailed information about imidazole glycerol phosphate synthase, go to the full flat file.
Word Map on EC 4.3.1.B2
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4.3.1.B2
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glutaminase
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ammonia
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amidotransferase
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maritima
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thermotoga
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allostery
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cyclase
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prfar
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ribonucleotide
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heterodimeric
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bienzyme
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aicar
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millisecond
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5-aminoimidazole-4-carboxamide
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betaalpha8-barrels
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v-type
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half-barrels
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timescale
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ribotide
- 4.3.1.B2
- glutaminase
- ammonia
-
amidotransferase
- maritima
-
thermotoga
-
allostery
- cyclase
-
prfar
- ribonucleotide
-
heterodimeric
-
bienzyme
- aicar
-
millisecond
- 5-aminoimidazole-4-carboxamide
-
betaalpha8-barrels
-
v-type
-
half-barrels
-
timescale
- ribotide
Reaction
Synonyms
HIS7, IGP synthase, IGPS, ImGP synthase
ECTree
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General Information
General Information on EC 4.3.1.B2 - imidazole glycerol phosphate synthase
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metabolism
physiological function
the enzyme represents a junction between histidine biosynthesis and de novo purine biosynthesis
key metabolic enzyme,which links amino acid and nucleottide biosynthesis. It uses the substrates glutamine and N'-[(5-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide to catalyze the closure of the imidazole ring within histidine biosynthesis and additionally provides 5-aminoimidazole-4-carboxamide ribotide for use in the de novo synthesis of purines
metabolism
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the enzyme catalyzes the fifth step in the histidine biosynthetic pathway located at the branch point to de novo purine biosynthesis
metabolism
the enzyme links histidine and de novo purine biosynthesis
metabolism
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key metabolic enzyme,which links amino acid and nucleottide biosynthesis. It uses the substrates glutamine and N'-[(5-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide to catalyze the closure of the imidazole ring within histidine biosynthesis and additionally provides 5-aminoimidazole-4-carboxamide ribotide for use in the de novo synthesis of purines
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metabolism
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the enzyme links histidine and de novo purine biosynthesis
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metabolism
Thermus thermophilus HB8 / ATCC 27634 / DSM 579
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the enzyme catalyzes the fifth step in the histidine biosynthetic pathway located at the branch point to de novo purine biosynthesis
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