4.1.2.43: 3-hexulose-6-phosphate synthase

This is an abbreviated version!
For detailed information about 3-hexulose-6-phosphate synthase, go to the full flat file.

Reaction

Synonyms

3-hexulose phosphate synthase, 3-hexulose-6-phosphate formaldehyde lyase, 3-hexulose-6-phosphate synthase, 3-hexulose-phosphate synthase, 3-hexulosephosphate synthase, D-arabino-3-hexulose 6-phosphate formaldehyde lyase, D-arabino-3-hexulose 6-phosphate formaldehyde-lyase, Fae-Hps, hexose phosphate synthase, hexulose-6-phosphate synthase, HPS, HPS-aldolase, HPS-PHI, HPS/PHI

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.43 3-hexulose-6-phosphate synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	Activating Compound
2492	AA Sequence
4	Application
1	CAS Registry Number
15	Cloned(Commentary)
1	Crystallization (Commentary)
22	General Information
28	Inhibitors
2	kcat/KM [mM/s]
43	KM Value [mM]
81	Metals/Ions
38	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
249	Organism
11	Pathway
4	PDB ID
8	pH Optimum
2	pH Stability
1	pI Value
20	Protein Variants
17	Purification (Commentary)
1	Reaction
2	Reaction Type
88	Reference
24	Specific Activity [micromol/min/mg]
4	Storage Stability
126	Substrates and Products (Substrate)
38	Subunits
152	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
14	Temperature Stability [°C]
4	Turnover Number [1/s]

Inhibitors

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Inhibitors on EC 4.1.2.43 - 3-hexulose-6-phosphate synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Inhibitor Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

ADP

Methylotuvimicrobium alcaliphilum

-

in the presence of 1 mM ADP, the enzyme retains 37% activity

747156

AMP

Methylotuvimicrobium alcaliphilum

-

complete inhibition at 1 mM AMP

747156

ATP

Methylotuvimicrobium alcaliphilum

-

in the presence of 1 mM ATP, the enzyme retains 86% activity

747156

Ca2+

Methylococcus capsulatus

-

49% inhibition at 1 mM

684946

Cu2+

3 entries

D-ribulose 5-phosphate

Bacillus sp. (in: Bacteria)

-

commercial D-ribulose 5-phosphate inhibits the enzyme

694003

EDTA

4 entries

Glutaraldehyde

Methylomonas aminofaciens

-

22% inhibition at 4 mM

691118

glyceraldehyde

Methylomonas aminofaciens

-

13% inhibition at 4 mM

691118

glycolaldehyde

Methylomonas aminofaciens

-

49% inhibition at 4 mM

691118

glycolic acid

Mycobacterium gastri

-

glycolic acid inhibits the enzyme competitively with respect to formaldehyde

690311

glyoxylate

Methylomonas aminofaciens

-

12% inhibition at 4 mM

691118

Hg2+

Methylomonas aminofaciens

-

81% inhibition with 1 mM Hg2+

691118

methylglyoxal

Methylomonas aminofaciens

-

26% inhibition at 4 mM

691118

Ni2+

Methylococcus capsulatus

-

64% inhibition at 1 mM

684946

o-phenanthroline

Mycobacterium gastri

-

the enzyme is completely inhibited by the presence of 2 mM o-phenanthroline

694004

Pb2+

Methylomonas aminofaciens

-

48% inhibition with 1 mM Pb2+

691118

phosphate

Methylotuvimicrobium alcaliphilum

-

in the presence of 1 mM phosphate, the enzyme retains 95% activity

747156

Tiron

Mycobacterium gastri

-

the enzyme is completely inhibited by the presence of 2 mM tiron

694004

additional information

4 entries

-

Cu2+

Acidomonas methanolica

-

1 mM Cu2+ is inhibitory, and the effect is partly abolished by Mg2+

694005

Cu2+

Methylococcus capsulatus

-

24% inhibition at 1 mM

684946

Cu2+

Methylomonas aminofaciens

-

45% inhibition with 1 mM Cu2+

691118

EDTA

Bacillus sp. (in: Bacteria)

-

-

694003

EDTA

Methylomonas aminofaciens

-

the enzyme is completely inhibited in the presence of EDTA, but the activity is restored depending on the amount of MgC12 supplemented

691118

EDTA

Methylomonas sp.

-

complete inhibition at 10 mM

690565

EDTA

Mycobacterium gastri

-

the enzyme is completely inhibited by the presence of 2 mM EDTA

694004

additional information

Methylococcus capsulatus

-

not inhibited by ATP, ADP, AMP, NADH, D-fructose 6-phosphate, and phosphoenolpyruvate

684946

-

additional information

Methylomonas sp.

-

not influenced by NaBH4

690565

-

additional information

Methylotuvimicrobium alcaliphilum

-

not inhibited by diphosphate

747156

-

additional information

Mycobacterium gastri

-

the enzyme is inactivated irreversibly on dialysis against buffer without Mg2+

694004

-